Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
2R01DK045416-05
Application #
2144652
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1992-09-30
Project End
2000-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Gan, Zhenji; Fu, Tingting; Kelly, Daniel P et al. (2018) Skeletal muscle mitochondrial remodeling in exercise and diseases. Cell Res 28:969-980
Zhang, Xiaolei; Trevino, Michelle B; Wang, Miao et al. (2018) Impaired Mitochondrial Energetics Characterize Poor Early Recovery of Muscle Mass Following Hind Limb Unloading in Old Mice. J Gerontol A Biol Sci Med Sci 73:1313-1322
Lee, Samuel; Leone, Teresa C; Rogosa, Lisa et al. (2017) Skeletal muscle PGC-1? signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice. Am J Physiol Endocrinol Metab 312:E394-E406
Vega, Rick B; Kelly, Daniel P (2017) Cardiac nuclear receptors: architects of mitochondrial structure and function. J Clin Invest 127:1155-1164
Vega, Rick B; Konhilas, John P; Kelly, Daniel P et al. (2017) Molecular Mechanisms Underlying Cardiac Adaptation to Exercise. Cell Metab 25:1012-1026
Ahn, Byungyong; Soundarapandian, Mangala M; Sessions, Hampton et al. (2016) MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling. J Clin Invest 126:3567-79
Liang, Xijun; Liu, Lin; Fu, Tingting et al. (2016) Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle. J Biol Chem 291:25306-25318
Liu, Jing; Liang, Xijun; Zhou, Danxia et al. (2016) Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med 8:1212-1228
Dorn 2nd, Gerald W; Vega, Rick B; Kelly, Daniel P (2015) Mitochondrial biogenesis and dynamics in the developing and diseased heart. Genes Dev 29:1981-91
Ciron, Carine; Zheng, Lu; Bobela, Wojciech et al. (2015) PGC-1? activity in nigral dopamine neurons determines vulnerability to ?-synuclein. Acta Neuropathol Commun 3:16

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