Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK046409-03
Application #
2145620
Study Section
Metabolism Study Section (MET)
Project Start
1993-12-01
Project End
1997-11-30
Budget Start
1995-12-15
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Wedgwood, Kyle C A; Satin, Leslie S (2018) Six degrees of depolarization: Comment on ""Network science of biological systems at different scales: A review"" by Marko Gosak et al. Phys Life Rev 24:136-139
Bertram, Richard; Satin, Leslie S; Sherman, Arthur S (2018) Closing in on the Mechanisms of Pulsatile Insulin Secretion. Diabetes 67:351-359
Gregg, Brigid E; Botezatu, Nathalie; Brill, Joshua D et al. (2018) Gestational exposure to metformin programs improved glucose tolerance and insulin secretion in adult male mouse offspring. Sci Rep 8:5745
Yildirim, Vehpi; Vadrevu, Suryakiran; Thompson, Benjamin et al. (2017) Upregulation of an inward rectifying K+ channel can rescue slow Ca2+ oscillations in K(ATP) channel deficient pancreatic islets. PLoS Comput Biol 13:e1005686
Kim, So Yoon; Lee, Ji-Hyeon; Merrins, Matthew J et al. (2017) Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary ?-Cell Dysfunction to Progressive Depletion of ?-Cell Mass and Diabetes. J Biol Chem 292:3841-3853
Satin, Leslie S; Parekh, Vishal S (2017) CFTR: Ferreting Out Its Role in Cystic Fibrosis-Related Diabetes. Endocrinology 158:3319-3321
Alejandro, Emilyn U; Bozadjieva, Nadejda; Blandino-Rosano, Manuel et al. (2017) Overexpression of Kinase-Dead mTOR Impairs Glucose Homeostasis by Regulating Insulin Secretion and Not ?-Cell Mass. Diabetes 66:2150-2162
Montemurro, Chiara; Vadrevu, Suryakiran; Gurlo, Tatyana et al. (2017) Cell cycle-related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line. Cell Cycle 16:2086-2099
Satin, Leslie S; Ha, Joon; Sherman, Arthur S (2016) Islets Transplanted Into the Eye: Do They Improve Our Insight Into Islet Adaptation to Insulin Resistance? Diabetes 65:2470-2
Wynn, Michelle L; Yates, Joel A; Evans, Charles R et al. (2016) RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells. J Biol Chem 291:13715-29

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