Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK047281-02
Application #
2146741
Study Section
Nutrition Study Section (NTN)
Project Start
1995-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Illinois at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Khan, Mateen A; Ma, Jia; Walden, William E et al. (2014) Rapid kinetics of iron responsive element (IRE) RNA/iron regulatory protein 1 and IRE-RNA/eIF4F complexes respond differently to metal ions. Nucleic Acids Res 42:6567-77
Pallesen, Leif J; Solodovnikova, Natalia; Sharma, Anil K et al. (2013) Interaction with Cfd1 increases the kinetic lability of FeS on the Nbp35 scaffold. J Biol Chem 288:23358-67
Netz, Daili J A; Pierik, Antonio J; Stümpfig, Martin et al. (2012) A bridging [4Fe-4S] cluster and nucleotide binding are essential for function of the Cfd1-Nbp35 complex as a scaffold in iron-sulfur protein maturation. J Biol Chem 287:12365-78
Sharma, Anil K; Pallesen, Leif J; Spang, Robert J et al. (2010) Cytosolic iron-sulfur cluster assembly (CIA) system: factors, mechanism, and relevance to cellular iron regulation. J Biol Chem 285:26745-51
Khan, Mateen A; Walden, William E; Goss, Dixie J et al. (2009) Direct Fe2+ sensing by iron-responsive messenger RNA:repressor complexes weakens binding. J Biol Chem 284:30122-8
Selezneva, Anna I; Cavigiolio, Giorgio; Theil, Elizabeth C et al. (2006) Crystallization and preliminary X-ray diffraction analysis of iron regulatory protein 1 in complex with ferritin IRE RNA. Acta Crystallogr Sect F Struct Biol Cryst Commun 62:249-52
Walden, William E; Selezneva, Anna I; Dupuy, Jerome et al. (2006) Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA. Science 314:1903-8
Bondar, Tanya; Mirkin, Ekaterina V; Ucker, David S et al. (2003) Schizosaccharomyces pombe Ddb1 is functionally linked to the replication checkpoint pathway. J Biol Chem 278:37006-14
Roy, Amit; Solodovnikova, Natalia; Nicholson, Tracy et al. (2003) A novel eukaryotic factor for cytosolic Fe-S cluster assembly. EMBO J 22:4826-35
Brown, Nina M; Kennedy, M Claire; Antholine, William E et al. (2002) Detection of a [3Fe-4S] cluster intermediate of cytosolic aconitase in yeast expressing iron regulatory protein 1. Insights into the mechanism of Fe-S cluster cycling. J Biol Chem 277:7246-54

Showing the most recent 10 out of 13 publications