Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK048218-03S1
Application #
2148371
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1996-05-15
Project End
1997-04-30
Budget Start
1996-05-15
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Cox, Marc B; Riggs, Daniel L; Hessling, Martin et al. (2007) FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity. Mol Endocrinol 21:2956-67
Riggs, Daniel L; Cox, Marc B; Tardif, Heather L et al. (2007) Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling. Mol Cell Biol 27:8658-69
Tranguch, Susanne; Wang, Haibin; Daikoku, Takiko et al. (2007) FKBP52 deficiency-conferred uterine progesterone resistance is genetic background and pregnancy stage specific. J Clin Invest 117:1824-34
Tranguch, Susanne; Smith, David F; Dey, Sudhansu K (2006) Progesterone receptor requires a co-chaperone for signalling in uterine biology and implantation. Reprod Biomed Online 13:651-60
Denny, Wesley B; Prapapanich, Viravan; Smith, David F et al. (2005) Structure-function analysis of squirrel monkey FK506-binding protein 51, a potent inhibitor of glucocorticoid receptor activity. Endocrinology 146:3194-201
Daikoku, Takiko; Tranguch, Susanne; Friedman, David B et al. (2005) Proteomic analysis identifies immunophilin FK506 binding protein 4 (FKBP52) as a downstream target of Hoxa10 in the periimplantation mouse uterus. Mol Endocrinol 19:683-97
Riggs, Daniel L; Cox, Marc B; Cheung-Flynn, Joyce et al. (2004) Functional specificity of co-chaperone interactions with Hsp90 client proteins. Crit Rev Biochem Mol Biol 39:279-95
Nelson, Gregory M; Prapapanich, Viravan; Carrigan, Patricia E et al. (2004) The heat shock protein 70 cochaperone hip enhances functional maturation of glucocorticoid receptor. Mol Endocrinol 18:1620-30
Smith, David F (2004) Tetratricopeptide repeat cochaperones in steroid receptor complexes. Cell Stress Chaperones 9:109-21
Cheung-Flynn, Joyce; Roberts, Patricia J; Riggs, Daniel L et al. (2003) C-terminal sequences outside the tetratricopeptide repeat domain of FKBP51 and FKBP52 cause differential binding to Hsp90. J Biol Chem 278:17388-94

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