Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK048549-11
Application #
2148918
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1989-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Dehnadi, Abbas; Benedict Cosimi, A; Neal Smith, Rex et al. (2017) Prophylactic orthosteric inhibition of leukocyte integrin CD11b/CD18 prevents long-term fibrotic kidney failure in cynomolgus monkeys. Nat Commun 8:13899
Camarata, Troy D; Weaver, Grant C; Vasilyev, Alexandr et al. (2015) Negative Regulation of TGF? Signaling by Stem Cell Antigen-1 Protects against Ischemic Acute Kidney Injury. PLoS One 10:e0129561
Wu, Qing; Zhang, Jiaojiao; Koh, Wonshill et al. (2015) Talin1 is required for cardiac Z-disk stabilization and endothelial integrity in zebrafish. FASEB J 29:4989-5005
Zhang, Jiaojiao; Yuan, Shipeng; Vasilyev, Aleksandr et al. (2015) The transcriptional coactivator Taz regulates proximodistal patterning of the pronephric tubule in zebrafish. Mech Dev 138 Pt 3:328-35
Van Agthoven, Johannes F; Xiong, Jian-Ping; Alonso, José Luis et al. (2014) Structural basis for pure antagonism of integrin ?V?3 by a high-affinity form of fibronectin. Nat Struct Mol Biol 21:383-8
Adair, Brian D; Altintas, Mehmet M; Möller, Clemens C et al. (2014) Structure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy. J Am Soc Nephrol 25:1465-73
Palmyre, Aurélien; Lee, Jeongeun; Ryklin, Gennadiy et al. (2014) Collective epithelial migration drives kidney repair after acute injury. PLoS One 9:e101304
Adair, Brian D; Xiong, Jian-Ping; Alonso, José Luis et al. (2013) EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane. PLoS One 8:e57951
Yu, Chih-Chuan; Fornoni, Alessia; Weins, Astrid et al. (2013) Abatacept in B7-1-positive proteinuric kidney disease. N Engl J Med 369:2416-23
Frohlich, Else M; Alonso, José Luis; Borenstein, Jeffrey T et al. (2013) Topographically-patterned porous membranes in a microfluidic device as an in vitro model of renal reabsorptive barriers. Lab Chip 13:2311-9

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