Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK049126-02
Application #
2016895
Study Section
Endocrinology Study Section (END)
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-09-25
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Pinto, Vitor M S; Minakhina, Svetlana; Qiu, Shuiqing et al. (2017) Naturally Occurring Amino Acids in Helix 10 of the Thyroid Hormone Receptor Mediate Isoform-Specific TH Gene Regulation. Endocrinology 158:3067-3078
Wondisford, Fredric E (2015) A direct role for thyroid hormone in development of the adrenal cortex. Endocrinology 156:1939-40
Aninye, Irene O; Matsumoto, Shunichi; Sidhaye, Aniket R et al. (2014) Circadian regulation of Tshb gene expression by Rev-Erb? (NR1D1) and nuclear corepressor 1 (NCOR1). J Biol Chem 289:17070-7
Ortiga-Carvalho, Tânia M; Sidhaye, Aniket R; Wondisford, Fredric E (2014) Thyroid hormone receptors and resistance to thyroid hormone disorders. Nat Rev Endocrinol 10:582-91
Paik, Elizabeth J; Mahony, Shaun; White, Richard M et al. (2013) A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports 1:425-36
Chiamolera, Maria I; Sidhaye, Aniket R; Matsumoto, Shunichi et al. (2012) Fundamentally distinct roles of thyroid hormone receptor isoforms in a thyrotroph cell line are due to differential DNA binding. Mol Endocrinol 26:926-39
Costa-e-Sousa, Ricardo H; Astapova, Inna; Ye, Felix et al. (2012) The thyroid axis is regulated by NCoR1 via its actions in the pituitary. Endocrinology 153:5049-57
Wondisford, Fredric E (2011) A new medical therapy for Cushing disease? J Clin Invest 121:4621-3
Richter, Claus-Peter; Munscher, Adrian; Machado, Danielle Santana et al. (2011) Complete activation of thyroid hormone receptor ýý by T3 is essential for normal cochlear function and morphology in mice. Cell Physiol Biochem 28:997-1008
Machado, Danielle S; Sabet, Amin; Santiago, Leticia A et al. (2009) A thyroid hormone receptor mutation that dissociates thyroid hormone regulation of gene expression in vivo. Proc Natl Acad Sci U S A 106:9441-6

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