Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK052852-06S1
Application #
6820429
Study Section
Endocrinology Study Section (END)
Program Officer
Haft, Carol R
Project Start
1997-09-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
6
Fiscal Year
2004
Total Cost
$71,618
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Haeusler, Rebecca A; McGraw, Timothy E; Accili, Domenico (2018) Biochemical and cellular properties of insulin receptor signalling. Nat Rev Mol Cell Biol 19:31-44
Waldhart, Althea N; Dykstra, Holly; Peck, Anderson S et al. (2017) Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin. Cell Rep 19:2005-2013
Brumfield, Alexandria; Chaudhary, Natasha; McGraw, Timothy E (2017) Secretion of Adipsin as an Assay to Measure Flux from the Endoplasmic Reticulum (ER). Bio Protoc 7:
Vazirani, Reema P; Verma, Akanksha; Sadacca, L Amanda et al. (2016) Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance. Diabetes 65:1577-89
Bruno, Joanne; Brumfield, Alexandria; Chaudhary, Natasha et al. (2016) SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes. J Cell Biol 214:61-76
Chaudhary, Natasha; Gonzalez, Eva; Chang, Sung-Hee et al. (2016) Adenovirus Protein E4-ORF1 Activation of PI3 Kinase Reveals Differential Regulation of Downstream Effector Pathways in Adipocytes. Cell Rep 17:3305-3318
Kajno, Esi; McGraw, Timothy E; Gonzalez, Eva (2015) Development of a new model system to dissect isoform specific Akt signalling in adipocytes. Biochem J 468:425-34
Antonescu, Costin N; McGraw, Timothy E; Klip, Amira (2014) Reciprocal regulation of endocytosis and metabolism. Cold Spring Harb Perspect Biol 6:a016964
Sadacca, L Amanda; Bruno, Joanne; Wen, Jennifer et al. (2013) Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs. Mol Biol Cell 24:2544-57
Wu, Ning; Zheng, Bin; Shaywitz, Adam et al. (2013) AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1. Mol Cell 49:1167-75

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