Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK054165-03
Application #
2906249
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
May, Michael K
Project Start
1997-09-30
Project End
2001-08-31
Budget Start
1999-09-01
Budget End
2000-08-31
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Mount Sinai School of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
114400633
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Soler, Dellys M; Ghosh, Ayantika; Chen, Frank et al. (2014) A single element in the 3'UTR of the apical sodium-dependent bile acid transporter controls both stabilization and destabilization of mRNA. Biochem J 462:547-53
Ghosh, Ayantika; Chen, Frank; Banerjee, Swati et al. (2014) c-Fos mediates repression of the apical sodium-dependent bile acid transporter by fibroblast growth factor-19 in mice. Am J Physiol Gastrointest Liver Physiol 306:G163-71
Chen, Frank; Shyu, Ann-Bin; Shneider, Benjamin L (2011) Hu antigen R and tristetraprolin: counter-regulators of rat apical sodium-dependent bile acid transporter by way of effects on messenger RNA stability. Hepatology 54:1371-8
Chen, Frank; Ellis, Ewa; Strom, Stephen C et al. (2010) ATPase Class I Type 8B Member 1 and protein kinase C zeta induce the expression of the canalicular bile salt export pump in human hepatocytes. Pediatr Res 67:183-7
Annaba, Fadi; Ma, Ke; Kumar, Pradeep et al. (2010) Ileal apical Na+-dependent bile acid transporter ASBT is upregulated in rats with diabetes mellitus induced by low doses of streptozotocin. Am J Physiol Gastrointest Liver Physiol 299:G898-906
Sinha, Jyoti; Chen, Frank; Miloh, Tamir et al. (2008) beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes. Am J Physiol Gastrointest Liver Physiol 295:G996-G1003
Frankenberg, Tamara; Miloh, Tamir; Chen, Frank Y et al. (2008) The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor. Hepatology 48:1896-905
Neimark, Ezequiel; Chen, Frank; Li, Xiaoping et al. (2006) c-Fos is a critical mediator of inflammatory-mediated repression of the apical sodium-dependent bile acid transporter. Gastroenterology 131:554-67
Frankenberg, Tamara; Rao, Anuradha; Chen, Frank et al. (2006) Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids. Am J Physiol Gastrointest Liver Physiol 290:G912-22
Pan, Debra H; Chen, Frank; Neimark, Ezequiel et al. (2005) FTF and LRH-1, two related but different transcription factors in human Caco-2 cells: their different roles in the regulation of bile acid transport. Biochim Biophys Acta 1732:31-7

Showing the most recent 10 out of 25 publications