Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK056997-01
Application #
6052394
Study Section
Special Emphasis Panel (ZRG1-GMA-2 (02))
Program Officer
Hamilton, Frank A
Project Start
2000-04-01
Project End
2004-12-31
Budget Start
2000-04-01
Budget End
2000-12-31
Support Year
1
Fiscal Year
2000
Total Cost
$223,340
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Zheng, G; Wu, S-P; Hu, Y et al. (2013) Corticosterone mediates stress-related increased intestinal permeability in a region-specific manner. Neurogastroenterol Motil 25:e127-39
Hu, Yongjun; Chen, Xiaomei; Smith, David E (2012) Species-dependent uptake of glycylsarcosine but not oseltamivir in Pichia pastoris expressing the rat, mouse, and human intestinal peptide transporter PEPT1. Drug Metab Dispos 40:1328-35
Hong, Shuangsong; Zheng, Gen; Wu, Xiaoyin et al. (2011) Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat. Gastroenterology 140:627-637.e4
Bitar, K; Greenwood-Van Meerveld, B; Saad, R et al. (2011) Aging and gastrointestinal neuromuscular function: insights from within and outside the gut. Neurogastroenterol Motil 23:490-501
Hong, S; Fan, J; Kemmerer, E S et al. (2009) Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. Gut 58:202-10
de Giorgio, Roberto; Volta, Umberto; Stanghellini, Vincenzo et al. (2008) Neurogenic chronic intestinal pseudo-obstruction: antineuronal antibody-mediated activation of autophagy via Fas. Gastroenterology 135:601-9
Hong, Shuangsong; Agresta, Laura; Guo, Chunfang et al. (2008) The TRPV1 receptor is associated with preferential stress in large dorsal root ganglion neurons in early diabetic sensory neuropathy. J Neurochem 105:1212-22
Lopez-Santiago, Luis F; Pertin, Marie; Morisod, Xavier et al. (2006) Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain. J Neurosci 26:7984-94
Hong, Shuangsong; Wiley, John W (2006) Altered expression and function of sodium channels in large DRG neurons and myelinated A-fibers in early diabetic neuropathy in the rat. Biochem Biophys Res Commun 339:652-60
Hong, Shuangsong; Wiley, John W (2005) Early painful diabetic neuropathy is associated with differential changes in the expression and function of vanilloid receptor 1. J Biol Chem 280:618-27

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