Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
7R01ES003179-12
Application #
3250323
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1983-03-01
Project End
1998-02-28
Budget Start
1993-11-01
Budget End
1994-02-28
Support Year
12
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Wadsworth Center
Department
Type
DUNS #
110521739
City
Menands
State
NY
Country
United States
Zip Code
12204
Kasten-Jolly, Jane; Lawrence, David A (2014) Lead modulation of macrophages causes multiorgan detrimental health effects. J Biochem Mol Toxicol 28:355-72
Lawrence, David A; McCabe Jr, Michael J (2002) Immunomodulation by metals. Int Immunopharmacol 2:293-302
Dyatlov, Vladimir A; Lawrence, David A (2002) Neonatal lead exposure potentiates sickness behavior induced by Listeria monocytogenes infection of mice. Brain Behav Immun 16:477-92
Snyder, J E; Filipov, N M; Parsons, P J et al. (2000) The efficiency of maternal transfer of lead and its influence on plasma IgE and splenic cellularity of mice. Toxicol Sci 57:87-94
Kim, D; Lawrence, D A (2000) Immunotoxic effects of inorganic lead on host resistance of mice with different circling behavior preferences. Brain Behav Immun 14:305-17
Heo, Y; Lee, W T; Lawrence, D A (1998) Differential effects of lead and cAMP on development and activities of Th1- and Th2-lymphocytes. Toxicol Sci 43:172-85
Kishikawa, H; Lawrence, D A (1998) Differential production of interleukin-6 in the brain and spleen of mice treated with lipopolysaccharide in the presence and absence of lead. J Toxicol Environ Health A 53:357-73
Heo, Y; Lee, W T; Lawrence, D A (1997) In vivo the environmental pollutants lead and mercury induce oligoclonal T cell responses skewed toward type-2 reactivities. Cell Immunol 179:185-95
Heo, Y; Parsons, P J; Lawrence, D A (1996) Lead differentially modifies cytokine production in vitro and in vivo. Toxicol Appl Pharmacol 138:149-57
Guo, T L; Mudzinski, S P; Lawrence, D A (1996) Regulation of HLA-DR and invariant chain expression by human peripheral blood mononuclear cells with lead, interferon-gamma, or interleukin-4. Cell Immunol 171:1-9

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