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Diani-Moore, Silvia; Ma, Yuliang; Gross, Steven S et al. (2014) Increases in levels of epoxyeicosatrienoic and dihydroxyeicosatrienoic acids (EETs and DHETs) in liver and heart in vivo by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and in hepatic EET:DHET ratios by cotreatment with TCDD and the soluble epoxide hydrolas Drug Metab Dispos 42:294-300
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Diani-Moore, Silvia; Zhang, Sheng; Ram, Payal et al. (2013) Aryl hydrocarbon receptor activation by dioxin targets phosphoenolpyruvate carboxykinase (PEPCK) for ADP-ribosylation via 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP). J Biol Chem 288:21514-25
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Diani-Moore, Silvia; Ma, Yuliang; Labitzke, Erin et al. (2011) Discovery and biological characterization of 1-(1H-indol-3-yl)-9H-pyrido[3,4-b]indole as an aryl hydrocarbon receptor activator generated by photoactivation of tryptophan by sunlight. Chem Biol Interact 193:119-28
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Diani-Moore, Silvia; Ram, Payal; Li, Xintian et al. (2010) Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect. J Biol Chem 285:38801-10
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Nair, Sudhir; Kekatpure, Vikram D; Judson, Benjamin L et al. (2009) UVR exposure sensitizes keratinocytes to DNA adduct formation. Cancer Prev Res (Phila) 2:895-902
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Labitzke, Erin M; Diani-Moore, Silvia; Rifkind, Arleen B (2007) Mitochondrial P450-dependent arachidonic acid metabolism by TCDD-induced hepatic CYP1A5;conversion of EETs to DHETs by mitochondrial soluble epoxide hydrolase. Arch Biochem Biophys 468:70-81
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Diani-Moore, Silvia; Labitzke, Erin; Brown, Richard et al. (2006) Sunlight generates multiple tryptophan photoproducts eliciting high efficacy CYP1A induction in chick hepatocytes and in vivo. Toxicol Sci 90:96-110
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Rifkind, Arleen B (2006) CYP1A in TCDD toxicity and in physiology-with particular reference to CYP dependent arachidonic acid metabolism and other endogenous substrates. Drug Metab Rev 38:291-335
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Diani-Moore, Silvia; Papachristou, Fotini; Labitzke, Erin et al. (2006) Induction of CYP1A and cyp2-mediated arachidonic acid epoxygenation and suppression of 20-hydroxyeicosatetraenoic acid by imidazole derivatives including the aromatase inhibitor vorozole. Drug Metab Dispos 34:1376-85
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Wood, Emily; Broekman, M Johan; Kirley, Terence L et al. (2002) Cell-type specificity of ectonucleotidase expression and upregulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Arch Biochem Biophys 407:49-62
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