Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES003719-03
Application #
3251289
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1985-06-15
Project End
1990-05-31
Budget Start
1987-06-01
Budget End
1988-05-31
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Stanford University
Department
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Gao, L; Whitlock Jr, J P (2001) Accessibility and activity of the promoter for a dioxin-inducible ecto-ATPase gene. Arch Biochem Biophys 392:270-8
Okino, S T; Whitlock Jr, J P (2000) The aromatic hydrocarbon receptor, transcription, and endocrine aspects of dioxin action. Vitam Horm 59:241-64
Whitlock Jr, J P (1999) Induction of cytochrome P4501A1. Annu Rev Pharmacol Toxicol 39:103-25
Gao, L; Dong, L; Whitlock Jr, J P (1998) A novel response to dioxin. Induction of ecto-ATPase gene expression. J Biol Chem 273:15358-65
Whitlock Jr, J P; Chichester, C H; Bedgood, R M et al. (1997) Induction of drug-metabolizing enzymes by dioxin. Drug Metab Rev 29:1107-27
Ma, Q; Whitlock Jr, J P (1997) A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Biol Chem 272:8878-84
Whitlock Jr, J P; Okino, S T; Dong, L et al. (1996) Cytochromes P450 5: induction of cytochrome P4501A1: a model for analyzing mammalian gene transcription. FASEB J 10:809-18
Ma, Q; Whitlock Jr, J P (1996) The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol Cell Biol 16:2144-50
Dong, L; Ma, Q; Whitlock Jr, J P (1996) DNA binding by the heterodimeric Ah receptor. Relationship to dioxin-induced CYP1A1 transcription in vivo. J Biol Chem 271:7942-8
Ma, Q; Dong, L; Whitlock Jr, J P (1995) Transcriptional activation by the mouse Ah receptor. Interplay between multiple stimulatory and inhibitory functions. J Biol Chem 270:12697-703

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