Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES004151-11
Application #
2153588
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1986-01-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California San Diego
Department
Pharmacology
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Sakurai, Toshiharu; Kudo, Masatoshi; Umemura, Atsushi et al. (2013) p38? inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of reactive oxygen species. Cancer Res 73:215-24
Cho, Ik-Hyun; Hong, Jinpyo; Suh, Eun Cheng et al. (2008) Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death. Brain 131:3019-33
Naugler, Willscott E; Sakurai, Toshiharu; Kim, Sunhwa et al. (2007) Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317:121-4
Temkin, Vladislav; Karin, Michael (2007) From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey. Immunol Rev 220:8-21
Solinas, Giovanni; Vilcu, Cristian; Neels, Jaap G et al. (2007) JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metab 6:386-97
Gallagher, Ewen; Enzler, Thomas; Matsuzawa, Atsushi et al. (2007) Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production. Nat Immunol 8:57-63
Gallagher, Ewen; Gao, Min; Liu, Yun-Cai et al. (2006) Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change. Proc Natl Acad Sci U S A 103:1717-22
Scheuner, Donalyn; Patel, Rupali; Wang, Feng et al. (2006) Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis. J Biol Chem 281:21458-68
Labuda, Tord; Christensen, Jan Pravsgaard; Rasmussen, Susanne et al. (2006) MEK kinase 1 is a negative regulator of virus-specific CD8(+) T cells. Eur J Immunol 36:2076-84
Tuncman, Gurol; Hirosumi, Jiro; Solinas, Giovanni et al. (2006) Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc Natl Acad Sci U S A 103:10741-6

Showing the most recent 10 out of 53 publications