Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES004862-05
Application #
2153796
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1990-07-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Public Health & Prev Medicine
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Boule, Lisbeth A; Burke, Catherine G; Jin, Guang-Bi et al. (2018) Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome. Sci Rep 8:1826
Franchini, Anthony M; Lawrence, B Paige (2018) Environmental exposures are hidden modifiers of anti-viral immunity. Curr Opin Toxicol 10:54-59
Boulé, Lisbeth A; Chapman, Timothy J; Hillman, Sara E et al. (2018) Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System of Mice. Toxicol Sci 163:639-654
Yee, Min; Domm, William; Gelein, Robert et al. (2017) Alternative Progenitor Lineages Regenerate the Adult Lung Depleted of Alveolar Epithelial Type 2 Cells. Am J Respir Cell Mol Biol 56:453-464
De Jesús Andino, Francisco; Lawrence, B Paige; Robert, Jacques (2017) Long term effects of carbaryl exposure on antiviral immune responses in Xenopus laevis. Chemosphere 170:169-175
Unnisa, Zeenath; Singh, Kameshwar P; Henry, Ellen C et al. (2016) Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem Cell Proliferation and Impacts Endosteal Niche Cells. Stem Cells Int 2016:4536187
Bennett, John A; Singh, Kameshwar P; Unnisa, Zeenath et al. (2015) Deficiency in Aryl Hydrocarbon Receptor (AHR) Expression throughout Aging Alters Gene Expression Profiles in Murine Long-Term Hematopoietic Stem Cells. PLoS One 10:e0133791
Singh, Kameshwar P; Bennett, John A; Casado, Fanny L et al. (2014) Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice. Stem Cells Dev 23:95-106
Gasiewicz, Thomas A; Singh, Kameshwar P; Bennett, J Allen (2014) The Ah receptor in stem cell cycling, regulation, and quiescence. Ann N Y Acad Sci 1310:44-50
Budinsky, R A; Schrenk, D; Simon, T et al. (2014) Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study. Crit Rev Toxicol 44:83-119

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