Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES004869-07
Application #
2153802
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1989-01-01
Project End
1995-05-31
Budget Start
1995-01-01
Budget End
1995-05-31
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Purdue University
Department
Nutrition
Type
Other Domestic Higher Education
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Smith, Kayla J; Murray, Iain A; Boyer, Jacob A et al. (2018) Allelic variants of the aryl hydrocarbon receptor differentially influence UVB-mediated skin inflammatory responses in SKH1 mice. Toxicology 394:27-34
Moyer, Benjamin J; Rojas, Itzel Y; Murray, Iain A et al. (2017) Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor. Toxicol Appl Pharmacol 323:74-80
Hubbard, Troy D; Murray, Iain A; Nichols, Robert G et al. (2017) Dietary Broccoli Impacts Microbial Community Structure and Attenuates Chemically Induced Colitis in Mice in an Ah receptor dependent manner. J Funct Foods 37:685-698
Murray, Iain A; Perdew, Gary H (2017) Ligand activation of the Ah receptor contributes to gastrointestinal homeostasis. Curr Opin Toxicol 2:15-23
Muku, Gulsum E; Lahoti, Tejas S; Murray, Iain A et al. (2017) Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses. Lab Invest 97:1471-1487
Murray, Iain A; Nichols, Robert G; Zhang, Limin et al. (2016) Expression of the aryl hydrocarbon receptor contributes to the establishment of intestinal microbial community structure in mice. Sci Rep 6:33969
Girer, Nathaniel G; Murray, Iain A; Omiecinski, Curtis J et al. (2016) Hepatic Aryl Hydrocarbon Receptor Attenuates Fibroblast Growth Factor 21 Expression. J Biol Chem 291:15378-87
Gutierrez, Mark A; Davis, Sonnet S; Rosko, Andrew et al. (2016) A novel AhR ligand, 2AI, protects the retina from environmental stress. Sci Rep 6:29025
Hubbard, Troy D; Murray, Iain A; Bisson, William H et al. (2016) Divergent Ah Receptor Ligand Selectivity during Hominin Evolution. Mol Biol Evol 33:2648-58
Zhang, Limin; Nichols, Robert G; Correll, Jared et al. (2015) Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation. Environ Health Perspect 123:679-88

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