Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES005980-04
Application #
2154822
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1993-06-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1998-05-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Georgia State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
837322494
City
Atlanta
State
GA
Country
United States
Zip Code
30302
Bridges, Christy C; Zalups, Rudolfs K (2017) Mechanisms involved in the transport of mercuric ions in target tissues. Arch Toxicol 91:63-81
Bridges, Christy C; Barfuss, Delon W; Joshee, Lucy et al. (2016) Compensatory Renal Hypertrophy and the Uptake of Cysteine S-Conjugates of Hg2+ in Isolated S2 Proximal Tubular Segments. Toxicol Sci 154:278-288
Zalups, Rudolfs K; Bridges, Christy C (2012) Relationships between the renal handling of DMPS and DMSA and the renal handling of mercury. Chem Res Toxicol 25:1825-38
Wang, Yanhua; Zalups, Rudolfs K; Barfuss, Delon W (2012) Luminal transport of thiol S-conjugates of methylmercury in isolated perfused rabbit renal proximal tubules. Toxicol Lett 213:203-10
Bridges, Christy C; Krasnikov, Boris F; Joshee, Lucy et al. (2012) New insights into the metabolism of organomercury compounds: mercury-containing cysteine S-conjugates are substrates of human glutamine transaminase K and potent inactivators of cystathionine ?-lyase. Arch Biochem Biophys 517:20-9
Bridges, Christy C; Joshee, Lucy; Zalups, Rudolfs K (2011) MRP2 and the handling of mercuric ions in rats exposed acutely to inorganic and organic species of mercury. Toxicol Appl Pharmacol 251:50-8
Wang, Yanhua; Zalups, Rudolfs K; Barfuss, Delon W (2010) Potential mechanisms involved in the absorptive transport of cadmium in isolated perfused rabbit renal proximal tubules. Toxicol Lett 193:61-8
Zalups, Rudolfs K; Bridges, Christy C (2010) Seventy-five percent nephrectomy and the disposition of inorganic mercury in 2,3-dimercaptopropanesulfonic acid-treated rats lacking functional multidrug-resistance protein 2. J Pharmacol Exp Ther 332:866-75
Bridges, Christy C; Zalups, Rudolfs K (2010) Transport of inorganic mercury and methylmercury in target tissues and organs. J Toxicol Environ Health B Crit Rev 13:385-410
Zalups, Rudolfs K; Bridges, Christy C (2009) MRP2 involvement in renal proximal tubular elimination of methylmercury mediated by DMPS or DMSA. Toxicol Appl Pharmacol 235:10-7

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