Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
2R01ES006484-04
Application #
2155334
Study Section
Special Emphasis Panel (ZRG4-ALTX-1)
Project Start
1993-09-01
Project End
2001-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Public Health & Prev Medicine
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Aremu, David A; Madejczyk, Michael S; Ballatori, Nazzareno (2008) N-acetylcysteine as a potential antidote and biomonitoring agent of methylmercury exposure. Environ Health Perspect 116:26-31
Clarkson, Thomas W; Vyas, Jayesh B; Ballatori, Nazzareno (2007) Mechanisms of mercury disposition in the body. Am J Ind Med 50:757-64
Hammond, Christine L; Marchan, Rosemarie; Krance, Suzanne M et al. (2007) Glutathione export during apoptosis requires functional multidrug resistance-associated proteins. J Biol Chem 282:14337-47
Madejczyk, Michael S; Aremu, David A; Simmons-Willis, Tracey A et al. (2007) Accelerated urinary excretion of methylmercury following administration of its antidote N-acetylcysteine requires Mrp2/Abcc2, the apical multidrug resistance-associated protein. J Pharmacol Exp Ther 322:378-84
Ballatori, Nazzareno; Henson, John H; Seward, David J et al. (2006) Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis. Comp Biochem Physiol B Biochem Mol Biol 144:167-79
Ballatori, Nazzareno; Hammond, Christine L; Cunningham, Jennifer B et al. (2005) Molecular mechanisms of reduced glutathione transport: role of the MRP/CFTR/ABCC and OATP/SLC21A families of membrane proteins. Toxicol Appl Pharmacol 204:238-55
Hammond, Christine L; Madejczyk, Michael S; Ballatori, Nazzareno (2004) Activation of plasma membrane reduced glutathione transport in death receptor apoptosis of HepG2 cells. Toxicol Appl Pharmacol 195:12-22
Seward, David J; Koh, Albert S; Boyer, James L et al. (2003) Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta. J Biol Chem 278:27473-82
Barlow, Brian K; Thiruchelvam, Mona J; Bennice, Lisa et al. (2003) Increased synaptosomal dopamine content and brain concentration of paraquat produced by selective dithiocarbamates. J Neurochem 85:1075-86
Lee, Thomas K; Koh, Albert S; Cui, Zhifeng et al. (2003) N-glycosylation controls functional activity of Oatp1, an organic anion transporter. Am J Physiol Gastrointest Liver Physiol 285:G371-81

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