Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES007685-02
Application #
2157135
Study Section
Special Emphasis Panel (SRC (R))
Project Start
1995-08-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Davis
Department
Public Health & Prev Medicine
Type
Schools of Earth Sciences/Natur
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Motta, Stefano; Minici, Claudia; Corrada, Dario et al. (2018) Ligand-induced perturbation of the HIF-2?:ARNT dimer dynamics. PLoS Comput Biol 14:e1006021
Bonati, Laura; Corrada, Dario; Tagliabue, Sara Giani et al. (2017) Molecular modeling of the AhR structure and interactions can shed light on ligand-dependent activation and transformation mechanisms. Curr Opin Toxicol 2:42-49
Corrada, Dario; Denison, Michael S; Bonati, Laura (2017) Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization. Mol Biosyst 13:981-990
Cheng, Yating; Jin, Un-Ho; Davidson, Laurie A et al. (2017) Editor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling. Toxicol Sci 155:458-473
Denison, Michael S; Faber, Samantha C (2017) And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor Responses. Curr Opin Toxicol 2:124-131
Bak, Su-Min; Iida, Midori; Soshilov, Anatoly A et al. (2017) Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major). Arch Toxicol 91:301-312
Brennan, Jennifer C; Bassal, Arzoo; He, Guochun et al. (2016) Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor ? and ? for improved detection of estrogenic/antiestrogenic chemicals. Environ Toxicol Chem 35:91-100
Corrada, Dario; Soshilov, Anatoly A; Denison, Michael S et al. (2016) Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation. PLoS Comput Biol 12:e1004981
Mexia, Nikitia; Gaitanis, Georgios; Velegraki, Aristea et al. (2015) Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast. Arch Biochem Biophys 571:16-20
Brennan, Jennifer C; He, Guochun; Tsutsumi, Tomoaki et al. (2015) Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits. Environ Sci Technol 49:11903-12

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