Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY005285-15
Application #
2159380
Study Section
Neurology C Study Section (NEUC)
Project Start
1988-09-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Gavert, Nancy; Ben-Shmuel, Amir; Lemmon, Vance et al. (2010) Nuclear factor-kappaB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells. J Cell Sci 123:2135-43
Tapanes-Castillo, Alexis; Weaver, Eli J; Smith, Robin P et al. (2010) A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice. Neurogenetics 11:53-71
Tyukhtenko, Sergiy; Deshmukh, Lalit; Kumar, Vineet et al. (2008) Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins. Biochemistry 47:4160-8
Bechara, Ahmad; Nawabi, Homaira; Moret, Frederic et al. (2008) FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse. EMBO J 27:1549-62
Buchser, William J; Pardinas, Jose R; Shi, Yan et al. (2006) 96-well electroporation method for transfection of mammalian central neurons. Biotechniques 41:619-24
Itoh, Kouichi; Shimono, Ken; Lemmon, Vance (2005) Dephosphorylation and internalization of cell adhesion molecule L1 induced by theta burst stimulation in rat hippocampus. Mol Cell Neurosci 29:245-9
Itoh, Kyoko; Fushiki, Shinji; Kamiguchi, Hiroyuki et al. (2005) Disrupted Schwann cell-axon interactions in peripheral nerves of mice with altered L1-integrin interactions. Mol Cell Neurosci 30:624-9
Cheng, Ling; Lemmon, Sandra; Lemmon, Vance (2005) RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activation. J Neurochem 94:1102-10
Newpher, Thomas M; Smith, Robin P; Lemmon, Vance et al. (2005) In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast. Dev Cell 9:87-98
Cheng, Ling; Itoh, Kouichi; Lemmon, Vance (2005) L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region. J Neurosci 25:395-403

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