Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY005314-14
Application #
2159395
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1983-09-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Morehouse School of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Cheng, Catherine; Nowak, Roberta B; Amadeo, Michael B et al. (2018) Tropomyosin 3.5 protects the F-actin networks required for tissue biomechanical properties. J Cell Sci 131:
Hu, Zhengping; Shi, Wen; Riquelme, Manuel A et al. (2017) Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation. Sci Rep 7:5298
Biswas, Sondip; Son, Alexander; Yu, Qili et al. (2016) Breakdown of interlocking domains may contribute to formation of membranous globules and lens opacity in ephrin-A5(-/-) mice. Exp Eye Res 145:130-139
Cheng, Catherine; Nowak, Roberta B; Biswas, Sondip K et al. (2016) Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells. Invest Ophthalmol Vis Sci 57:4084-99
Cheng, Catherine; Nowak, Roberta B; Gao, Junyuan et al. (2015) Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells. Am J Physiol Cell Physiol 308:C835-47
Biswas, Sondip K; Brako, Lawrence; Gu, Sumin et al. (2014) Regional changes of AQP0-dependent square array junction and gap junction associated with cortical cataract formation in the Emory mutant mouse. Exp Eye Res 127:132-42
Biswas, Sondip K; Brako, Lawrence; Lo, Woo-Kuen (2014) Massive formation of square array junctions dramatically alters cell shape but does not cause lens opacity in the cav1-KO mice. Exp Eye Res 125:9-19
Lo, Woo-Kuen; Biswas, Sondip K; Brako, Lawrence et al. (2014) Aquaporin-0 targets interlocking domains to control the integrity and transparency of the eye lens. Invest Ophthalmol Vis Sci 55:1202-12
Zhang, Cheng; Asnaghi, Laura; Gongora, Celine et al. (2011) A developmental defect in astrocytes inhibits programmed regression of the hyaloid vasculature in the mammalian eye. Eur J Cell Biol 90:440-8
Biswas, Sondip K; Lee, Jai Eun; Brako, Lawrence et al. (2010) Gap junctions are selectively associated with interlocking ball-and-sockets but not protrusions in the lens. Mol Vis 16:2328-41

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