Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY007559-09
Application #
2161570
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1988-03-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Physiology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
del Pilar Gomez, Maria; Nasi, Enrico (2005) A direct signaling role for phosphatidylinositol 4,5-bisphosphate (PIP2) in the visual excitation process of microvillar receptors. J Biol Chem 280:16784-9
del Pilar Gomez, Maria; Nasi, Enrico (2005) Calcium-independent, cGMP-mediated light adaptation in invertebrate ciliary photoreceptors. J Neurosci 25:2042-9
Gomez, Maria del Pilar; Nasi, Enrico (2005) On the gating mechanisms of the light-dependent conductance in Pecten hyperpolarizing photoreceptors: does light remove inactivation in voltage-dependent K channels? J Gen Physiol 125:455-64
Piccoli, Giuseppe; Del Pilar Gomez, Maria; Nasi, Enrico (2002) Role of protein kinase C in light adaptation of molluscan microvillar photoreceptors. J Physiol 543:481-94
Gomez, M P; Nasi, E (2000) Light transduction in invertebrate hyperpolarizing photoreceptors: possible involvement of a Go-regulated guanylate cyclase. J Neurosci 20:5254-63
Nasi, E; del Pilar Gomez, M (1999) Divalent cation interactions with light-dependent K channels. Kinetics of voltage-dependent block and requirement for an open pore. J Gen Physiol 114:653-72
Gomez, M P; Nasi, E (1997) Light adaptation in Pecten hyperpolarizing photoreceptors. Insensitivity to calcium manipulations. J Gen Physiol 109:371-84
Gomez, M P; Nasi, E (1997) Antagonists of the cGMP-gated conductance of vertebrate rods block the photocurrent in scallop ciliary photoreceptors. J Physiol 500 ( Pt 2):367-78
Gomez, M D; Nasi, E (1996) Ion permeation through light-activated channels in rhabdomeric photoreceptors. Role of divalent cations. J Gen Physiol 107:715-30
del Pilar Gomez, M; Nasi, E (1995) Activation of light-dependent K+ channels in ciliary invertebrate photoreceptors involves cGMP but not the IP3/Ca2+ cascade. Neuron 15:607-18

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