A program of research is proposed to use functional magnetic resonance imaging (FMRI) to analyze how visual information is organized and processed in human visual cortex. Using methods that have either been developed or refined by this group, nine visual cortical areas of interest will be identified in each subject using fMRI and displayed on a flatted cortical format.
Four aims will be pursued. First, how and where visual contours defined by different types of visual cues (luminance, hue, motion, etc.) are processed in visual cortex will be investigated. Second, changes in fMRI responses in response to large-field changes in luminance, color, and spatial frequency will be measured. Third, specific questions about visual motion processing will be addressed. Fourth, orientation sensitivity in different visual areas will be assessed by examining transient responses to changes in orientation.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY007980-09
Application #
2711016
Study Section
Special Emphasis Panel (ZRG1-VISA (01))
Project Start
1993-12-01
Project End
2001-06-30
Budget Start
1998-07-01
Budget End
1999-06-30
Support Year
9
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
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Mendola, J D; Dale, A M; Fischl, B et al. (1999) The representation of illusory and real contours in human cortical visual areas revealed by functional magnetic resonance imaging. J Neurosci 19:8560-72

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