Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY008694-02
Application #
3266040
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1991-07-01
Project End
1993-06-30
Budget Start
1992-07-01
Budget End
1993-06-30
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Emory University
Department
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Sun, Ru; Peng, Shaomin; Chen, Xiang et al. (2008) Diffusible retinal secretions regulate the expression of tight junctions and other diverse functions of the retinal pigment epithelium. Mol Vis 14:2237-62
Cong, Lidan; Sun, Dawei; Zhang, Zhongyu et al. (2008) A novel rabbit model for studying RPE transplantation. Invest Ophthalmol Vis Sci 49:4115-25
Rizzolo, Lawrence J (2007) Development and role of tight junctions in the retinal pigment epithelium. Int Rev Cytol 258:195-234
Rizzolo, Lawrence J; Chen, Xiang; Weitzman, Matthew et al. (2007) Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier. Mol Vis 13:1259-73
Luo, Yan; Fukuhara, Masayuki; Weitzman, Matthew et al. (2006) Expression of JAM-A, AF-6, PAR-3 and PAR-6 during the assembly and remodeling of RPE tight junctions. Brain Res 1110:55-63
Luo, Yan; Zhuo, Yehong; Fukuhara, Masayuki et al. (2006) Effects of culture conditions on heterogeneity and the apical junctional complex of the ARPE-19 cell line. Invest Ophthalmol Vis Sci 47:3644-55
Rahner, Christoph; Fukuhara, Masayuki; Peng, Shaomin et al. (2004) The apical and basal environments of the retinal pigment epithelium regulate the maturation of tight junctions during development. J Cell Sci 117:3307-18
Peng, Shaomin; Rahner, Christoph; Rizzolo, Lawrence J (2003) Apical and basal regulation of the permeability of the retinal pigment epithelium. Invest Ophthalmol Vis Sci 44:808-17
Kojima, S; Rahner, C; Peng, S et al. (2002) Claudin 5 is transiently expressed during the development of the retinal pigment epithelium. J Membr Biol 186:81-8
Bumsted, K M; Rizzolo, L J; Barnstable, C J (2001) Defects in the MITF(mi/mi) apical surface are associated with a failure of outer segment elongation. Exp Eye Res 73:383-92

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