Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY008834-05
Application #
2162507
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1991-07-01
Project End
1997-02-28
Budget Start
1995-07-01
Budget End
1997-02-28
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Berkeley
Department
Other Health Professions
Type
Schools of Optometry/Ophthalmol
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Bhadange, Yogesh; Lautert, Jeferson; Li, Shimin et al. (2018) Hypoxia and the Prolyl Hydroxylase Inhibitor FG-4592 Protect Corneal Endothelial Cells From Mechanical and Perioperative Surgical Stress. Cornea 37:501-507
Li, Shimin; Hundal, Karmjot Singh; Chen, Xingjuan et al. (2018) R125H, W240S, C386R, and V507I SLC4A11 mutations associated with corneal endothelial dystrophy affect the transporter function but not trafficking in PS120 cells. Exp Eye Res 180:86-91
Zhang, Wenlin; Ogando, Diego G; Kim, Edward T et al. (2017) Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model. Invest Ophthalmol Vis Sci 58:3723-3731
Zhang, Wenlin; Li, Hongde; Ogando, Diego G et al. (2017) Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium. EBioMedicine 16:292-301
Li, Shimin; Kim, Edward; Bonanno, Joseph A (2016) Fluid transport by the cornea endothelium is dependent on buffering lactic acid efflux. Am J Physiol Cell Physiol 311:C116-26
Zhang, Wenlin; Ogando, Diego G; Bonanno, Joseph A et al. (2015) Human SLC4A11 Is a Novel NH3/H+ Co-transporter. J Biol Chem 290:16894-905
Li, Shimin; Nguyen, Tracy T; Bonanno, Joseph A (2014) CD147 required for corneal endothelial lactate transport. Invest Ophthalmol Vis Sci 55:4673-81
Robertson, Danielle M; Alexander, Larry J; Bonanno, Joseph A et al. (2014) Cornea and ocular surface disease: application of cutting-edge optometric research. Optom Vis Sci 91:S3-16
Jalimarada, Supriya S; Ogando, Diego G; Bonanno, Joseph A (2014) Loss of ion transporters and increased unfolded protein response in Fuchs' dystrophy. Mol Vis 20:1668-79
Jalimarada, Supriya S; Ogando, Diego G; Vithana, Eranga N et al. (2013) Ion transport function of SLC4A11 in corneal endothelium. Invest Ophthalmol Vis Sci 54:4330-40

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