Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY009056-06
Application #
2162666
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1991-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Gordon, Marion K; DeSantis-Rodrigues, Andrea; Hahn, Rita et al. (2016) The molecules in the corneal basement membrane zone affected by mustard exposure suggest potential therapies. Ann N Y Acad Sci 1378:158-165
DeSantis-Rodrigues, Andrea; Chang, Yoke-Chen; Hahn, Rita A et al. (2016) ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure. Invest Ophthalmol Vis Sci 57:1687-98
Chang, Yoke-Chen; Wang, James D; Hahn, Rita A et al. (2014) Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard. Toxicol Appl Pharmacol 280:236-44
Chang, Yoke-Chen; Wang, James D; Svoboda, Kathy K et al. (2013) Sulfur mustard induces an endoplasmic reticulum stress response in the mouse ear vesicant model. Toxicol Appl Pharmacol 268:178-87
Zheng, Ruijin; Po, Iris; Mishin, Vladimir et al. (2013) The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard. Toxicol Appl Pharmacol 272:345-55
Chao, Ming Wei; Po, Iris P; Laumbach, Robert J et al. (2012) DEP induction of ROS in capillary-like endothelial tubes leads to VEGF-A expression. Toxicology 297:34-46
Black, Adrienne T; Gordon, Marion K; Heck, Diane E et al. (2011) UVB light regulates expression of antioxidants and inflammatory mediators in human corneal epithelial cells. Biochem Pharmacol 81:873-80
Chao, Ming-Wei; Kozlosky, John; Po, Iris P et al. (2011) Diesel exhaust particle exposure causes redistribution of endothelial tube VE-cadherin. Toxicology 279:73-84
Gordon, Marion K; Desantis, Andrea; Deshmukh, Manjeet et al. (2010) Doxycycline hydrogels as a potential therapy for ocular vesicant injury. J Ocul Pharmacol Ther 26:407-19
Gordon, Marion K; Hahn, Rita A (2010) Collagens. Cell Tissue Res 339:247-57

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