Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009676-05
Application #
2163347
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1992-08-01
Project End
1998-02-28
Budget Start
1996-08-01
Budget End
1998-02-28
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Genetics
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Mizeracka, Karolina; DeMaso, Christina R; Cepko, Constance L (2013) Notch1 is required in newly postmitotic cells to inhibit the rod photoreceptor fate. Development 140:3188-97
Emerson, Mark M; Surzenko, Natalia; Goetz, Jillian J et al. (2013) Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors. Dev Cell 26:59-72
Mizeracka, Karolina; Trimarchi, Jeffrey M; Stadler, Michael B et al. (2013) Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling. Dev Dyn 242:1147-59
Emerson, Mark M; Cepko, Constance L (2011) Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors. Dev Biol 360:241-55
Cherry, Timothy J; Wang, Sui; Bormuth, Ingo et al. (2011) NeuroD factors regulate cell fate and neurite stratification in the developing retina. J Neurosci 31:7365-79
Bienvenu, Frédéric; Jirawatnotai, Siwanon; Elias, Joshua E et al. (2010) Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature 463:374-8
Jadhav, Ashutosh P; Roesch, Karin; Cepko, Constance L (2009) Development and neurogenic potential of Muller glial cells in the vertebrate retina. Prog Retin Eye Res 28:249-62
Kim, Douglas S; Matsuda, Takahiko; Cepko, Constance L (2008) A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression. J Neurosci 28:7748-64
Damiani, Devid; Alexander, John J; O'Rourke, Jason R et al. (2008) Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci 28:4878-87
Morrow, Eric M; Chen, C-M Amy; Cepko, Constance L (2008) Temporal order of bipolar cell genesis in the neural retina. Neural Dev 3:2

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