Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009756-07
Application #
6627031
Study Section
Special Emphasis Panel (ZRG1-SSS-R (03))
Program Officer
Shen, Grace L
Project Start
1995-08-01
Project End
2004-08-31
Budget Start
2003-01-01
Budget End
2004-08-31
Support Year
7
Fiscal Year
2003
Total Cost
$273,000
Indirect Cost

  Institution

Name
University of Texas Sw Medical Center Dallas
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390

  Publications

Tripathi, Trivendra; Abdi, Mahshid; Alizadeh, Hassan (2014) Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells. Invest Ophthalmol Vis Sci 55:3912-21
Tripathi, Trivendra; Alizadeh, Hassan (2014) Significance of arachidonic acid in ocular infections and inflammation. Inflamm Cell Signal 1:
Alizadeh, Hassan; Tripathi, Trivendra; Abdi, Mahshid et al. (2014) Pathogenic strains of Acanthamoeba are recognized by TLR4 and initiated inflammatory responses in the cornea. PLoS One 9:e92375
Tripathi, Trivendra; Alizadeh, Hassan (2014) Role of protease-activated receptors 2 (PAR2) in ocular infections and inflammation. Receptors Clin Investig 1:
Tripathi, Trivendra; Abdi, Mahshid; Alizadeh, Hassan (2013) Role of phospholipase A? (PLA?) inhibitors in attenuating apoptosis of the corneal epithelial cells and mitigation of Acanthamoeba keratitis. Exp Eye Res 113:182-91
Tripathi, Trivendra; Smith, Ashley Dawn; Abdi, Mahshid et al. (2012) Acanthamoeba-cytopathic protein induces apoptosis and proinflammatory cytokines in human corneal epithelial cells by cPLA2? activation. Invest Ophthalmol Vis Sci 53:7973-82
Alizadeh, Hassan; Neelam, Sudha; Cavanagh, H Dwight (2009) Amoebicidal activities of alexidine against 3 pathogenic strains of acanthamoeba. Eye Contact Lens 35:1-5
Alizadeh, Hassan; Li, Haochuan; Neelam, Sudha et al. (2008) Modulation of corneal and stromal matrix metalloproteinase by the mannose-induced Acanthamoeba cytolytic protein. Exp Eye Res 87:286-91
Alizadeh, Hassan; Neelam, Sudha; Niederkorn, Jerry Y (2007) Role of activated macrophages in Acanthamoeba keratitis. J Parasitol 93:1114-20
Alizadeh, Hassan; Neelam, Sudha; Niederkorn, Jerry Y (2007) Effect of immunization with the mannose-induced Acanthamoeba protein and Acanthamoeba plasminogen activator in mitigating Acanthamoeba keratitis. Invest Ophthalmol Vis Sci 48:5597-604

Showing the most recent 10 out of 36 publications