Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY010568-03
Application #
2164529
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1994-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1999-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Chien, Hsin; Alston, Christine I; Dix, Richard D (2018) Suppressor of Cytokine Signaling 1 (SOCS1) and SOCS3 Are Stimulated within the Eye during Experimental Murine Cytomegalovirus Retinitis in Mice with Retrovirus-Induced Immunosuppression. J Virol 92:
Alston, Christine I; Dix, Richard D (2017) Reduced frequency of murine cytomegalovirus retinitis in C57BL/6 mice correlates with low levels of suppressor of cytokine signaling (SOCS)1 and SOCS3 expression within the eye during corticosteroid-induced immunosuppression. Cytokine 97:38-41
Blalock, Emily L; Chien, Hsin; Dix, Richard D (2013) Murine cytomegalovirus downregulates interleukin-17 in mice with retrovirus-induced immunosuppression that are susceptible to experimental cytomegalovirus retinitis. Cytokine 61:862-75
Cousins, Scott W; Espinosa-Heidmann, Diego G; Miller, Daniel M et al. (2012) Macrophage activation associated with chronic murine cytomegalovirus infection results in more severe experimental choroidal neovascularization. PLoS Pathog 8:e1002671
Blalock, Emily L; Chien, Hsin; Dix, Richard D (2012) Systemic reduction of interleukin-4 or interleukin-10 fails to reduce the frequency or severity of experimental cytomegalovirus retinitis in mice with retrovirus-induced immunosuppression. Ophthalmol Eye Dis 4:79-90
Chien, Hsin; Dix, Richard D (2012) Evidence for multiple cell death pathways during development of experimental cytomegalovirus retinitis in mice with retrovirus-induced immunosuppression: apoptosis, necroptosis, and pyroptosis. J Virol 86:10961-78
Buckner, Anissa E; Dix, Richard D (2006) Nicotine treatment alters NF-kappaB expression in human cytomegalovirus-infected ARPE-19 cells. Curr Eye Res 31:191-8
Dix, R D; Cousins, S W (2005) Cell-mediated cytotoxicity of murine cytomegalovirus-infected target cells allows for release of residual infectious virus. Arch Virol 150:797-803
Dix, Richard D; Cousins, Scott W (2004) Susceptibility to murine cytomegalovirus retinitis during progression of MAIDS: correlation with intraocular levels of tumor necrosis factor-alpha and interferon-gamma. Curr Eye Res 29:173-80
Dix, R D; Ekworomadu, C O; Hernandez, E et al. (2004) Perforin knockout mice, but not mice with MAIDS, show protection against experimental cytomegalovirus retinitis after adoptive transfer of immune cells with a functional perforin cytotoxic pathway. Arch Virol 149:2235-44

Showing the most recent 10 out of 21 publications