Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
1R01EY011522-01
Application #
2165831
Study Section
Special Emphasis Panel (ZRG1-VISC (01))
Project Start
1996-08-01
Project End
1997-04-30
Budget Start
1996-08-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Washington
Department
Biochemistry
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Sato, Shinya; Peshenko, Igor V; Olshevskaya, Elena V et al. (2018) GUCY2D Cone-Rod Dystrophy-6 Is a ""Phototransduction Disease"" Triggered by Abnormal Calcium Feedback on Retinal Membrane Guanylyl Cyclase 1. J Neurosci 38:2990-3000
Lim, Sunghyuk; Cudia, Diana; Yu, Qinhong et al. (2018) Chemical shift assignments of retinal degeneration 3 protein (RD3). Biomol NMR Assign 12:167-170
Lim, Sunghyuk; Roseman, Graham; Peshenko, Igor et al. (2018) Retinal guanylyl cyclase activating protein 1 forms a functional dimer. PLoS One 13:e0193947
Vinberg, Frans; Peshenko, Igor V; Chen, Jeannie et al. (2018) Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors. J Biol Chem 293:7457-7465
Boye, Sanford L; Olshevskaya, Elena V; Peshenko, Igor V et al. (2016) Functional study of two biochemically unusual mutations in GUCY2D Leber congenital amaurosis expressed via adenoassociated virus vector in mouse retinas. Mol Vis 22:1342-1351
Dizhoor, Alexander M; Olshevskaya, Elena V; Peshenko, Igor V (2016) The R838S Mutation in Retinal Guanylyl Cyclase 1 (RetGC1) Alters Calcium Sensitivity of cGMP Synthesis in the Retina and Causes Blindness in Transgenic Mice. J Biol Chem 291:24504-24516
Lim, Sunghyuk; Peshenko, Igor V; Olshevskaya, Elena V et al. (2016) Structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) Mutant V77E in a Ca2+-free/Mg2+-bound Activator State. J Biol Chem 291:4429-41
Yang, Sufang; Dizhoor, Alexander; Wilson, David J et al. (2016) GCAP1, Rab6, and HSP27: Novel Autoantibody Targets in Cancer-Associated Retinopathy and Autoimmune Retinopathy. Transl Vis Sci Technol 5:1
Peshenko, Igor V; Olshevskaya, Elena V; Dizhoor, Alexander M (2016) Functional Study and Mapping Sites for Interaction with the Target Enzyme in Retinal Degeneration 3 (RD3) Protein. J Biol Chem 291:19713-23
Boye, Sanford L; Peterson, James J; Choudhury, Shreyasi et al. (2015) Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1. Hum Gene Ther 26:575-92

Showing the most recent 10 out of 64 publications