Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
1R01EY011542-01
Application #
2165850
Study Section
Special Emphasis Panel (ZRG1-VISC (01))
Project Start
1996-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Schuld, Nathan J; Hussong, Stacy A; Kapphahn, Rebecca J et al. (2015) Immunoproteasome deficiency protects in the retina after optic nerve crush. PLoS One 10:e0126768
McPherson, Scott W; Heuss, Neal D; Gregerson, Dale S (2012) Regulation of CD8(+) T Cell Responses to Retinal Antigen by Local FoxP3(+) Regulatory T Cells. Front Immunol 3:166
Ferrington, Deborah A; Gregerson, Dale S (2012) Immunoproteasomes: structure, function, and antigen presentation. Prog Mol Biol Transl Sci 109:75-112
Heuss, Neal D; Lehmann, Ute; Norbury, Christopher C et al. (2012) Local activation of dendritic cells alters the pathogenesis of autoimmune disease in the retina. J Immunol 188:1191-200
McPherson, Scott W; Heuss, Neal D; Lehman, Ute et al. (2011) Generation of Regulatory T Cells to Antigen Expressed in the Retina. Curr Immunol Rev 7:344-349
Lehmann, Ute; Heuss, Neal D; McPherson, Scott W et al. (2010) Dendritic cells are early responders to retinal injury. Neurobiol Dis 40:177-84
McPherson, Scott W; Heuss, Neal D; Gregerson, Dale S (2009) Lymphopenia-induced proliferation is a potent activator for CD4+ T cell-mediated autoimmune disease in the retina. J Immunol 182:969-79
Gregerson, Dale S; Heuss, Neal D; Lehmann, Ute et al. (2009) Peripheral induction of tolerance by retinal antigen expression. J Immunol 183:814-22
Gregerson, Dale S; Heuss, Neal D; Lehmann, Ute et al. (2008) Evidence for extrathymic generation of regulatory T cells specific for a retinal antigen. Ophthalmic Res 40:154-9
Ferrington, Deborah A; Hussong, Stacy A; Roehrich, Heidi et al. (2008) Immunoproteasome responds to injury in the retina and brain. J Neurochem 106:158-69

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