Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM021941-22
Application #
2173839
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1978-02-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cornell University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Bird, Jeremy G; Strobel, Eric J; Roberts, Jeffrey W (2016) A universal transcription pause sequence is an element of initiation factor ?70-dependent pausing. Nucleic Acids Res 44:6732-40
Strobel, Eric J; Roberts, Jeffrey W (2015) Two transcription pause elements underlie a ?70-dependent pause cycle. Proc Natl Acad Sci U S A 112:E4374-80
Strobel, Eric J; Roberts, Jeffrey W (2014) Regulation of promoter-proximal transcription elongation: enhanced DNA scrunching drives ?Q antiterminator-dependent escape from a ?70-dependent pause. Nucleic Acids Res 42:5097-108
Liu, Xiaoqiu; Jiang, Huifeng; Gu, Zhenglong et al. (2013) High-resolution view of bacteriophage lambda gene expression by ribosome profiling. Proc Natl Acad Sci U S A 110:11928-33
Perdue, Sarah A; Roberts, Jeffrey W (2010) A backtrack-inducing sequence is an essential component of Escherichia coli ?(70)-dependent promoter-proximal pausing. Mol Microbiol 78:636-50
Hatoum, Asma; Roberts, Jeffrey (2008) Prevalence of RNA polymerase stalling at Escherichia coli promoters after open complex formation. Mol Microbiol 68:17-28
Roberts, Jeffrey W; Shankar, Smita; Filter, Joshua J (2008) RNA polymerase elongation factors. Annu Rev Microbiol 62:211-33
Davydova, Elena K; Santangelo, Thomas J; Rothman-Denes, Lucia B (2007) Bacteriophage N4 virion RNA polymerase interaction with its promoter DNA hairpin. Proc Natl Acad Sci U S A 104:7033-8
Park, Joo-Seop; Roberts, Jeffrey W (2006) Role of DNA bubble rewinding in enzymatic transcription termination. Proc Natl Acad Sci U S A 103:4870-5
Holmes, Shannon F; Santangelo, Thomas J; Cunningham, Candice K et al. (2006) Kinetic investigation of Escherichia coli RNA polymerase mutants that influence nucleotide discrimination and transcription fidelity. J Biol Chem 281:18677-83

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