Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM022086-20
Application #
2173863
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1978-05-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
20
Fiscal Year
1996
Total Cost
Indirect Cost
Name
College of Staten Island
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10314
Fracchiolla, Katrina E; Cohen, Leah S; Arshava, Boris et al. (2015) Structural characterization of triple transmembrane domain containing fragments of a yeast G protein-coupled receptor in an organic?:?aqueous environment by solution-state NMR spectroscopy. J Pept Sci 21:212-22
Mathew, Elizabeth; Ding, Fa-Xiang; Naider, Fred et al. (2013) Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast. Protein Eng Des Sel 26:59-71
Kim, Kyeong-Man; Lee, Yong-Hun; Akal-Strader, Ayca et al. (2012) Multiple regulatory roles of the carboxy terminus of Ste2p a yeast GPCR. Pharmacol Res 65:31-40
Mathew, Elizabeth; Bajaj, Anshika; Connelly, Sara M et al. (2011) Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p. J Mol Biol 409:513-28
Cohen, L S; Arshava, B; Neumoin, A et al. (2011) Comparative NMR analysis of an 80-residue G protein-coupled receptor fragment in two membrane mimetic environments. Biochim Biophys Acta 1808:2674-84
Cohen, Leah S; Becker, Jeffrey M; Naider, Fred (2010) Biosynthesis of peptide fragments of eukaryotic GPCRs in Escherichia coli by directing expression into inclusion bodies. J Pept Sci 16:213-8
Neumoin, Alexey; Cohen, Leah S; Arshava, Boris et al. (2009) Structure of a double transmembrane fragment of a G-protein-coupled receptor in micelles. Biophys J 96:3187-96
Naider, Fred; Neumoin, Alexey; Arshava, Boris et al. (2009) Structural studies on large fragments of G protein coupled receptors. Adv Exp Med Biol 611:309-10
Umanah, George; Huang, Li-Yin; Schultz, Peter G et al. (2009) Incorporation of the unnatural amino acid p-benzoyl-L-phenylalanine (Bpa) into a G protein-coupled receptor in its native context. Adv Exp Med Biol 611:333-5
Mor, Amit; Segal, Eugenia; Mester, Brenda et al. (2009) Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies. Biochemistry 48:3288-303

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