Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM023037-15
Application #
2174036
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1988-01-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
North Carolina State University Raleigh
Department
Biochemistry
Type
Schools of Earth Sciences/Natur
DUNS #
City
Raleigh
State
NC
Country
United States
Zip Code
27695

  Publications

Xiao, Xingqing; Agris, Paul F; Hall, Carol K (2015) Designing peptide sequences in flexible chain conformations to bind RNA: a search algorithm combining Monte Carlo, self-consistent mean field and concerted rotation techniques. J Chem Theory Comput 11:740-52
Harris, Kimberly A; Bobay, Benjamin G; Sarachan, Kathryn L et al. (2015) NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions. J Biol Chem 290:20032-43
Halvorsen, Ken; Agris, Paul F (2014) Cross-platform comparison of nucleic acid hybridization: toward quantitative reference standards. Anal Biochem 465:127-33
Spears, Jessica L; Xiao, Xingqing; Hall, Carol K et al. (2014) Amino acid signature enables proteins to recognize modified tRNA. Biochemistry 53:1125-33
Rodriguez-Hernandez, Annia; Spears, Jessica L; Gaston, Kirk W et al. (2013) Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position. J Mol Biol 425:3888-906
Harris, Kimberly A; Shekhtman, Alexander; Agris, Paul F (2013) Specific RNA-protein interactions detected with saturation transfer difference NMR. RNA Biol 10:1307-11
Vendeix, Franck A P; Murphy 4th, Frank V; Cantara, William A et al. (2012) Human tRNA(Lys3)(UUU) is pre-structured by natural modifications for cognate and wobble codon binding through keto-enol tautomerism. J Mol Biol 416:467-85
Graham, William D; Barley-Maloney, Lise; Stark, Caren J et al. (2011) Functional recognition of the modified human tRNALys3(UUU) anticodon domain by HIV's nucleocapsid protein and a peptide mimic. J Mol Biol 410:698-715
Bilbille, Yann; Gustilo, Estella M; Harris, Kimberly A et al. (2011) The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons. J Mol Biol 406:257-74
Harris, Kimberly A; Jones, Victoria; Bilbille, Yann et al. (2011) YrdC exhibits properties expected of a subunit for a tRNA threonylcarbamoyl transferase. RNA 17:1678-87

Showing the most recent 10 out of 50 publications