Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM023875-18
Application #
2174166
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1992-08-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106

  Publications

Roberts, M C; Mickelson, J R; Patterson, E E et al. (2001) Autosomal dominant canine malignant hyperthermia is caused by a mutation in the gene encoding the skeletal muscle calcium release channel (RYR1). Anesthesiology 95:716-25
Coleman, K R; Braden, G A; Willingham, M C et al. (1999) Vitaxin, a humanized monoclonal antibody to the vitronectin receptor (alphavbeta3), reduces neointimal hyperplasia and total vessel area after balloon injury in hypercholesterolemic rabbits. Circ Res 84:1268-76
Zaloga, G P; Roberts, P R; Black, K W et al. (1997) Carnosine is a novel peptide modulator of intracellular calcium and contractility in cardiac cells. Am J Physiol 272:H462-8
Sudo, R T; Nelson, T E (1997) Changes in ryanodine-induced contractures by stimulus frequency in malignant hyperthermia susceptible and malignant hyperthermia nonsusceptible dog skeletal muscle. J Pharmacol Exp Ther 282:1331-6
Zaloga, G P; Roberts, P R; Nelson, T E (1996) Carnosine: a novel peptide regulator of intracellular calcium and contractility in cardiac muscle. New Horiz 4:26-35
Nelson, T E; Lin, M; Zapata-Sudo, G et al. (1996) Dantrolene sodium can increase or attenuate activity of skeletal muscle ryanodine receptor calcium release channel. Clinical implications. Anesthesiology 84:1368-79
Wedel, D J; Nelson, T E (1994) Malignant hyperthermia--diagnostic dilemma: false-negative contracture responses with halothane and caffeine alone. Anesth Analg 78:787-92
Hawkes, M J; Nelson, T E; Hamilton, S L (1992) [3H]ryanodine as a probe of changes in the functional state of the Ca(2+)-release channel in malignant hyperthermia. J Biol Chem 267:6702-9
Nelson, T E (1992) Halothane effects on human malignant hyperthermia skeletal muscle single calcium-release channels in planar lipid bilayers. Anesthesiology 76:588-95
Nelson, T E; Lin, M; Volpe, P (1991) Evidence for intraluminal Ca++ regulatory site defect in sarcoplasmic reticulum from malignant hyperthermia pig muscle. J Pharmacol Exp Ther 256:645-9

Showing the most recent 10 out of 19 publications