Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM024887-17
Application #
2174341
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1981-08-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
17
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Studley, W K; Yamaguchi, M; Hatefi, Y et al. (1999) Phylogenetic analyses of proton-translocating transhydrogenases. Microb Comp Genomics 4:173-86
Yamaguchi, M; Hatefi, Y (1997) High cyclic transhydrogenase activity catalyzed by expressed and reconstituted nucleotide-binding domains of Rhodospirillum rubrum transhydrogenase. Biochim Biophys Acta 1318:225-34
Hatefi, Y; Yamaguchi, M (1996) Nicotinamide nucleotide transhydrogenase: a model for utilization of substrate binding energy for proton translocation. FASEB J 10:444-52
Yamaguchi, M; Hatefi, Y (1995) Proton-translocating nicotinamide nucleotide transhydrogenase of Escherichia coli. Involvement of aspartate 213 in the membrane-intercalating domain of the beta subunit in energy transduction. J Biol Chem 270:16653-9
Yamaguchi, M; Hatefi, Y (1995) Proton-translocating nicotinamide nucleotide transhydrogenase. Reconstitution of the extramembranous nucleotide-binding domains. J Biol Chem 270:28165-8
Milgrom, Y M; Hatefi, Y (1994) Studies on reconstitution of the Rhodospirillum rubrum nicotinamide nucleotide transhydrogenase. Biochem Mol Biol Int 34:1099-108
Yamaguchi, M; Hatefi, Y (1994) Energy-transducing nicotinamide nucleotide transhydrogenase: nucleotide sequences of the genes and predicted amino acid sequences of the subunits of the enzyme from Rhodospirillum rubrum. J Bioenerg Biomembr 26:435-45
Yamaguchi, M; Hatefi, Y (1993) Energy-transducing nicotinamide nucleotide transhydrogenase. Nucleotide binding properties of the purified enzyme and proteolytic fragments. J Biol Chem 268:17871-7
Yamaguchi, M; Hatefi, Y (1991) Mitochondrial energy-linked nicotinamide nucleotide transhydrogenase. Membrane topography of the bovine enzyme. J Biol Chem 266:5728-35
Yamaguchi, M; Hatefi, Y (1991) Mitochondrial energy-transducing nicotinamide nucleotide transhydrogenase. Purification and properties of the proteinase K-bisected enzyme. J Biol Chem 266:17020-5

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