Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM026165-15
Application #
2174634
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1987-01-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Pharmacology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Edin, Matthew L; Juliano, Rudy L (2005) Raf-1 serine 338 phosphorylation plays a key role in adhesion-dependent activation of extracellular signal-regulated kinase by epidermal growth factor. Mol Cell Biol 25:4466-75
Reddig, Peter J; Xu, Dong; Juliano, Rudy L (2005) Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarin. J Biol Chem 280:30994-1002
Alahari, Suresh K; Reddig, Peter J; Juliano, Rudy L (2004) The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK. EMBO J 23:2777-88
Laakko, Tonya; Juliano, Rudolph L (2003) Adhesion regulation of stromal cell-derived factor-1 activation of ERK in lymphocytes by phosphatases. J Biol Chem 278:31621-8
Juliano, R L (2002) Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annu Rev Pharmacol Toxicol 42:283-323
Howe, Alan K; Hogan, Brian P; Juliano, R L (2002) Regulation of vasodilator-stimulated phosphoprotein phosphorylation and interaction with Abl by protein kinase A and cell adhesion. J Biol Chem 277:38121-6
Lee, Jung Weon; Juliano, R L (2002) The alpha5beta1 integrin selectively enhances epidermal growth factor signaling to the phosphatidylinositol-3-kinase/Akt pathway in intestinal epithelial cells. Biochim Biophys Acta 1542:23-31
Aplin, Andrew E; Hogan, Brian P; Tomeu, Jeannie et al. (2002) Cell adhesion differentially regulates the nucleocytoplasmic distribution of active MAP kinases. J Cell Sci 115:2781-90
Aplin, A E; Stewart, S A; Assoian, R K et al. (2001) Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1. J Cell Biol 153:273-82
Howe, A K (2001) Cell adhesion regulates the interaction between Nck and p21-activated kinase. J Biol Chem 276:14541-4

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