Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM026449-19
Application #
2174719
Study Section
Special Emphasis Panel (ZRG2-MGN (Q1))
Project Start
1987-09-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109

  Publications

Zhao, Hui; Friedman, Richard D; Fournier, R E K (2007) The locus control region activates serpin gene expression through recruitment of liver-specific transcription factors and RNA polymerase II. Mol Cell Biol 27:5286-95
Marsden, Mark D; Fournier, R E K (2005) Organization and expression of the human serpin gene cluster at 14q32.1. Front Biosci 10:1768-78
Baxter, Euan W; Cummings, W Jason; Fournier, R E K (2005) Formation of a large, complex domain of histone hyperacetylation at human 14q32.1 requires the serpin locus control region. Nucleic Acids Res 33:3313-22
Namciu, Stephanie J; Friedman, Richard D; Marsden, Mark D et al. (2004) Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1. Mamm Genome 15:162-78
Namciu, Stephanie J; Fournier, R E K (2004) Human matrix attachment regions are necessary for the establishment but not the maintenance of transgene insulation in Drosophila melanogaster. Mol Cell Biol 24:10236-45
Marsden, Mark D; Fournier, R E K (2003) Chromosomal elements regulate gene activity and chromatin structure of the human serpin gene cluster at 14q32.1. Mol Cell Biol 23:3516-26
Antes, T J; Namciu, S J; Fournier, R E et al. (2001) The 5' boundary of the human apolipoprotein B chromatin domain in intestinal cells. Biochemistry 40:6731-42
Rollini, P; Fournier, R E (2000) Differential regulation of gene activity and chromatin structure within the human serpin gene cluster at 14q32.1 in macrophage microcell hybrids. Nucleic Acids Res 28:1767-77
Rollini, P; Xu, L; Fournier, R E (1999) Partial activation of gene activity and chromatin remodeling of the human 14q32.1 serpin gene cluster by HNF-1 alpha and HNF-4 in fibroblast microcell hybrids. Somat Cell Mol Genet 25:207-21
Rollini, P; Fournier, R E (1999) The HNF-4/HNF-1alpha transactivation cascade regulates gene activity and chromatin structure of the human serine protease inhibitor gene cluster at 14q32.1. Proc Natl Acad Sci U S A 96:10308-13

Showing the most recent 10 out of 46 publications