Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM026782-18
Application #
2174804
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1987-02-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Indiana University Bloomington
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
006046700
City
Bloomington
State
IN
Country
United States
Zip Code
47401
Doherty, Joanne R; Yang, Chunying; Scott, Kristen E N et al. (2014) Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. Cancer Res 74:908-20
Dossey, Aaron T; Whitaker, John M; Dancel, Maria Cristina A et al. (2012) Defensive spiroketals from Asceles glaber (Phasmatodea): absolute configuration and effects on ants and mosquitoes. J Chem Ecol 38:1105-15
Chen, Ming; Roush, William R (2011) Enantioconvergent hydroboration of a racemic allene: enantioselective synthesis of (E)-ýý-stannyl-anti-homoallylic alcohols via aldehyde crotylboration. J Am Chem Soc 133:5744-7
Halvorsen, Geoff T; Roush, William R (2011) Stereoselective Synthesis of the Decahydrofluorene Core of the Hirsutellones. Tetrahedron Lett 52:2072-2075
Sun, Huikai; Abbott, Jason R; Roush, William R (2011) Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin. Org Lett 13:2734-7
Chen, Ming; Ess, Daniel H; Roush, William R (2010) Enantioselective synthesis of (E)-delta-stannyl homoallylic alcohols via aldehyde allylboration using alpha-stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift. J Am Chem Soc 132:7881-3
Chen, Ming; Roush, William R (2010) Highly (E)-selective BF(3).Et(2)O-promoted allylboration of chiral nonracemic alpha-substituted allylboronates and analysis of the origin of stereocontrol. Org Lett 12:2706-9
Chen, Ming; Handa, Masaki; Roush, William R (2009) Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences. J Am Chem Soc 131:14602-3
Ess, Daniel H; Kister, Jeremy; Chen, Ming et al. (2009) Quantum-mechanical study of 10-R-9-borabicyclo[3.3.2]decane alkene hydroboration. J Org Chem 74:8626-37
Ess, Daniel H; Kister, Jeremy; Chen, Ming et al. (2009) Origin of thermodynamic versus kinetic control of allene hydroboration with 9-borabicyclo[3.3.1]nonane and 10(R)-trimethylsilyl-9-borabicyclo[3.3.2]decane. Org Lett 11:5538-41

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