Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM027003-27
Application #
2174865
Study Section
Biochemistry Study Section (BIO)
Project Start
1979-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
27
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Purdue University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907

  Publications

Waheed, Abdul; Hassan, Md Imtaiyaz; Etten, Robert L Van et al. (2008) Human seminal proteinase and prostate-specific antigen are the same protein. J Biosci 33:195-207
Gustafson, Christin L T; Stauffacher, Cynthia V; Hallenga, Klaas et al. (2005) Solution structure of the low-molecular-weight protein tyrosine phosphatase from Tritrichomonas foetus reveals a flexible phosphate binding loop. Protein Sci 14:2515-25
Asthagiri, D; Liu, Tiqing; Noodleman, Louis et al. (2004) On the role of the conserved aspartate in the hydrolysis of the phosphocysteine intermediate of the low molecular weight tyrosine phosphatase. J Am Chem Soc 126:12677-84
Akerud, Tomas; Thulin, Eva; Van Etten, Robert L et al. (2002) Intramolecular dynamics of low molecular weight protein tyrosine phosphatase in monomer-dimer equilibrium studied by NMR: a model for changes in dynamics upon target binding. J Mol Biol 322:137-52
Thomas, Christin L; McKinnon, Evangeline; Granger, Bruce L et al. (2002) Kinetic and spectroscopic studies of Tritrichomonas foetus low-molecular weight phosphotyrosyl phosphatase. Hydrogen bond networks and electrostatic effects. Biochemistry 41:15601-9
Asthagiri, Dilipkumar; Dillet, Valerie; Liu, Tiqing et al. (2002) Density functional study of the mechanism of a tyrosine phosphatase: I. Intermediate formation. J Am Chem Soc 124:10225-35
Waheed, Abdul; Van Etten, Robert L (2002) Protection of prostatic acid phosphatase activity in human serum samples by plasmin inhibitors. Clin Chim Acta 320:127-31
Kikawa, Keith D; Vidale, Derika R; Van Etten, Robert L et al. (2002) Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation. J Biol Chem 277:39274-9
Waheed, A; Van Etten, R L (2001) The biosynthesis of prostate-specific antigen in non prostatic cell lines. Clin Biochem 34:617-21
Wang, S; Stauffacher, C V; Van Etten, R L (2000) Structural and mechanistic basis for the activation of a low-molecular weight protein tyrosine phosphatase by adenine. Biochemistry 39:1234-42

Showing the most recent 10 out of 61 publications