Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM027242-17
Application #
2174903
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1980-01-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Universidad Autonoma de Madrid
Department
Type
DUNS #
City
Madrid
State
Country
Spain
Zip Code
Perez-Lago, Laura; Salas, Margarita; Camacho, Ana (2005) A precise DNA bend angle is essential for the function of the phage phi29 transcriptional regulator. Nucleic Acids Res 33:126-34
Asensio, Juan Luis; Albert, Armando; Munoz-Espin, Daniel et al. (2005) Structure of the functional domain of phi29 replication organizer: insights into oligomerization and dna binding. J Biol Chem 280:20730-9
Bravo, Alicia; Serrano-Heras, Gemma; Salas, Margarita (2005) Compartmentalization of prokaryotic DNA replication. FEMS Microbiol Rev 29:25-47
Meijer, Wilfried J J; Castilla-Llorente, Virginia; Villar, Laurentino et al. (2005) Molecular basis for the exploitation of spore formation as survival mechanism by virulent phage phi29. EMBO J 24:3647-57
Truniger, Veronica; Bonnin, Ana; Lazaro, Jose M et al. (2005) Involvement of the ""linker"" region between the exonuclease and polymerization domains of phi29 DNA polymerase in DNA and TP binding. Gene 348:89-99
Gonzalez-Huici, Victor; Salas, Margarita; Hermoso, Jose M (2004) Genome wide, supercoiling-dependent in vivo binding of a viral protein involved in DNA replication and transcriptional control. Nucleic Acids Res 32:2306-14
Munoz-Espin, Daniel; Mateu, Mauricio G; Villar, Laurentino et al. (2004) Phage phi29 DNA replication organizer membrane protein p16.7 contains a coiled coil and a dimeric, homeodomain-related, functional domain. J Biol Chem 279:50437-45
Rodriguez, Irene; Lazaro, Jose M; Salas, Margarita et al. (2004) phi29 DNA polymerase-terminal protein interaction. Involvement of residues specifically conserved among protein-primed DNA polymerases. J Mol Biol 337:829-41
Truniger, Veronica; Lazaro, Jose M; Salas, Margarita (2004) Function of the C-terminus of phi29 DNA polymerase in DNA and terminal protein binding. Nucleic Acids Res 32:361-70
Camacho, Ana; Salas, Margarita (2004) Molecular interplay between RNA polymerase and two transcriptional regulators in promoter switch. J Mol Biol 336:357-68

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