Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM028216-21
Application #
2175129
Study Section
Genetics Study Section (GEN)
Project Start
1980-07-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Queens College
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Flushing
State
NY
Country
United States
Zip Code
11367

  Publications

Ran, Fulai; Gadura, Nidhi; Michels, Corinne A (2010) Hsp90 cochaperone Aha1 is a negative regulator of the Saccharomyces MAL activator and acts early in the chaperone activation pathway. J Biol Chem 285:13850-62
Ran, Fulai; Bali, Mehtap; Michels, Corinne A (2008) Hsp90/Hsp70 chaperone machine regulation of the Saccharomyces MAL-activator as determined in vivo using noninducible and constitutive mutant alleles. Genetics 179:331-43
Gadura, Nidhi; Michels, Corinne A (2006) Sequences in the N-terminal cytoplasmic domain of Saccharomyces cerevisiae maltose permease are required for vacuolar degradation but not glucose-induced internalization. Curr Genet 50:101-14
Gadura, Nidhi; Robinson, Lucy C; Michels, Corinne A (2006) Glc7-Reg1 phosphatase signals to Yck1,2 casein kinase 1 to regulate transport activity and glucose-induced inactivation of Saccharomyces maltose permease. Genetics 172:1427-39
Wang, Xin; Michels, Corinne A (2004) Mutations in SIN4 and RGR1 cause constitutive expression of MAL structural genes in Saccharomyces cerevisiae. Genetics 168:747-57
Bali, Mehtap; Zhang, Bin; Morano, Kevin A et al. (2003) The Hsp90 molecular chaperone complex regulates maltose induction and stability of the Saccharomyces MAL gene transcription activator Mal63p. J Biol Chem 278:47441-8
Danzi, Sara E; Bali, Mehtap; Michels, Corinne A (2003) Clustered-charge to alanine scanning mutagenesis of the Mal63 MAL-activator C-terminal regulatory domain. Curr Genet 44:173-83
Wang, Xin; Bali, Mehtap; Medintz, Igor et al. (2002) Intracellular maltose is sufficient to induce MAL gene expression in Saccharomyces cerevisiae. Eukaryot Cell 1:696-703
Jiang, H; Tatchell, K; Liu, S et al. (2000) Protein phosphatase type-1 regulatory subunits Reg1p and Reg2p act as signal transducers in the glucose-induced inactivation of maltose permease in Saccharomyces cerevisiae. Mol Gen Genet 263:411-22
Hu, Z; Yue, Y; Jiang, H et al. (2000) Analysis of the mechanism by which glucose inhibits maltose induction of MAL gene expression in Saccharomyces. Genetics 154:121-32

Showing the most recent 10 out of 29 publications