Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM029182-09S1
Application #
3276708
Study Section
Genetics Study Section (GEN)
Project Start
1981-04-01
Project End
1991-06-30
Budget Start
1990-04-01
Budget End
1990-06-30
Support Year
9
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Chicago
Department
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Varela, Elisa; Schlecht, Ulrich; Moina, Anca et al. (2010) Mitotic expression of Spo13 alters M-phase progression and nucleolar localization of Cdc14 in budding yeast. Genetics 185:841-54
Tevzadze, Gela G; Pierce, Jessica V; Esposito, Rochelle Easton (2007) Genetic evidence for a SPO1-dependent signaling pathway controlling meiotic progression in yeast. Genetics 175:1213-27
Williams, Roy M; Primig, Michael; Washburn, Brian K et al. (2002) The Ume6 regulon coordinates metabolic and meiotic gene expression in yeast. Proc Natl Acad Sci U S A 99:13431-6
Washburn, B K; Esposito, R E (2001) Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast. Mol Cell Biol 21:2057-69
Rutkowski, L H; Esposito, R E (2000) Recombination can partially substitute for SPO13 in regulating meiosis I in budding yeast. Genetics 155:1607-21
Tevzadze, G G; Swift, H; Esposito, R E (2000) Spo1, a phospholipase B homolog, is required for spindle pole body duplication during meiosis in Saccharomyces cerevisiae. Chromosoma 109:72-85
Primig, M; Williams, R M; Winzeler, E A et al. (2000) The core meiotic transcriptome in budding yeasts. Nat Genet 26:415-23
Steber, C M; Esposito, R E (1995) UME6 is a central component of a developmental regulatory switch controlling meiosis-specific gene expression. Proc Natl Acad Sci U S A 92:12490-4
Anderson, S F; Steber, C M; Esposito, R E et al. (1995) UME6, a negative regulator of meiosis in Saccharomyces cerevisiae, contains a C-terminal Zn2Cys6 binuclear cluster that binds the URS1 DNA sequence in a zinc-dependent manner. Protein Sci 4:1832-43
McCarroll, R M; Esposito, R E (1994) SPO13 negatively regulates the progression of mitotic and meiotic nuclear division in Saccharomyces cerevisiae. Genetics 138:47-60

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