Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM029361-17
Application #
2175485
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1988-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Johnson, Kristen; Angelin-Duclos, Cristina; Park, Sinae et al. (2003) Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development. Mol Cell Biol 23:2438-50
Lin, Kuo-I; Angelin-Duclos, Cristina; Kuo, Tracy C et al. (2002) Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. Mol Cell Biol 22:4771-80
Shaffer, A L; Lin, Kuo I; Kuo, Tracy C et al. (2002) Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity 17:51-62
Angelin-Duclos, Cristina; Johnson, Kristen; Liao, Jerry et al. (2002) An interfering form of Blimp-1 increases IgM secreting plasma cells and blocks maturation of peripheral B cells. Eur J Immunol 32:3765-75
Rooney, J W; Calame, K L (2001) TIF1beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in the myelomonocytic cell line U937. Genes Dev 15:3023-38
Calame, K L (2001) Plasma cells: finding new light at the end of B cell development. Nat Immunol 2:1103-8
Piskurich, J F; Lin, K I; Lin, Y et al. (2000) BLIMP-I mediates extinction of major histocompatibility class II transactivator expression in plasma cells. Nat Immunol 1:526-32
Lin, K I; Lin, Y; Calame, K (2000) Repression of c-myc is necessary but not sufficient for terminal differentiation of B lymphocytes in vitro. Mol Cell Biol 20:8684-95
Berrier, A; Siu, G; Calame, K (1998) Transcription of a minimal promoter from the NF-IL6 gene is regulated by CREB/ATF and SP1 proteins in U937 promonocytic cells. J Immunol 161:2267-75
Angelin-Duclos, C; Calame, K (1998) Evidence that immunoglobulin VH-DJ recombination does not require germ line transcription of the recombining variable gene segment. Mol Cell Biol 18:6253-64

Showing the most recent 10 out of 43 publications