Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM029480-15
Application #
2175530
Study Section
Genetics Study Section (GEN)
Project Start
1989-08-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Balt CO Campus
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Baltimore
State
MD
Country
United States
Zip Code
21250
Manickam, Nandini; Joshi, Kartikeya; Bhatt, Monika J et al. (2016) Effects of tRNA modification on translational accuracy depend on intrinsic codon-anticodon strength. Nucleic Acids Res 44:1871-81
Nord, Stefan; Bhatt, Monika J; Tükenmez, Hasan et al. (2015) Mutations of ribosomal protein S5 suppress a defect in late-30S ribosomal subunit biogenesis caused by lack of the RbfA biogenesis factor. RNA 21:1454-68
Manickam, Nandini; Nag, Nabanita; Abbasi, Aleeza et al. (2014) Studies of translational misreading in vivo show that the ribosome very efficiently discriminates against most potential errors. RNA 20:9-15
Turkel, Sezai; Kaplan, Guliz; Farabaugh, Philip J (2011) Glucose signalling pathway controls the programmed ribosomal frameshift efficiency in retroviral-like element Ty3 in Saccharomyces cerevisiae. Yeast 28:799-808
Kramer, Emily B; Vallabhaneni, Haritha; Mayer, Lauren M et al. (2010) A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae. RNA 16:1797-808
Vallabhaneni, Haritha; Fan-Minogue, Hua; Bedwell, David M et al. (2009) Connection between stop codon reassignment and frequent use of shifty stop frameshifting. RNA 15:889-97
Vallabhaneni, Haritha; Farabaugh, Philip J (2009) Accuracy modulating mutations of the ribosomal protein S4-S5 interface do not necessarily destabilize the rps4-rps5 protein-protein interaction. RNA 15:1100-9
Kramer, Emily B; Farabaugh, Philip J (2007) The frequency of translational misreading errors in E. coli is largely determined by tRNA competition. RNA 13:87-96
Guarraia, Carla; Norris, Laura; Raman, Ana et al. (2007) Saturation mutagenesis of a +1 programmed frameshift-inducing mRNA sequence derived from a yeast retrotransposon. RNA 13:1940-7
Taliaferro, Dwayne L; Farabaugh, Philip J (2007) Testing constraints on rRNA bases that make nonsequence-specific contacts with the codon-anticodon complex in the ribosomal A site. RNA 13:1279-86

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