Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM029569-16
Application #
2175572
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1981-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Phillips, N F; Hsieh, P C; Kowalczyk, T H (1999) Polyphosphate glucokinase. Prog Mol Subcell Biol 23:101-25
Phillips, N F; Li, Z; Lindmark, D G (1997) Isolation of a pyrophosphate-dependent phosphofructokinase from Hexamita inflata. Mol Biochem Parasitol 90:377-80
Hsieh, P C; Kowalczyk, T H; Phillips, N F (1996) Kinetic mechanisms of polyphosphate glucokinase from Mycobacterium tuberculosis. Biochemistry 35:9772-81
Kowalczyk, T H; Horn, P J; Pan, W H et al. (1996) Initial rate and equilibrium isotope exchange studies on the ATP-dependent activity of polyphosphate Glucokinase from Propionibacterium shermanii. Biochemistry 35:6777-85
Hsieh, P C; Shenoy, B C; Samols, D et al. (1996) Cloning, expression, and characterization of polyphosphate glucokinase from Mycobacterium tuberculosis. J Biol Chem 271:4909-15
Hsieh, P C; Shenoy, B C; Jentoft, J E et al. (1993) Purification of polyphosphate and ATP glucose phosphotransferase from Mycobacterium tuberculosis H37Ra: evidence that poly(P) and ATP glucokinase activities are catalyzed by the same enzyme. Protein Expr Purif 4:76-84
Phillips, N F; Horn, P J; Wood, H G (1993) The polyphosphate- and ATP-dependent glucokinase from Propionibacterium shermanii: both activities are catalyzed by the same protein. Arch Biochem Biophys 300:309-19
Hsieh, P C; Shenoy, B C; Haase, F C et al. (1993) Involvement of tryptophan(s) at the active site of polyphosphate/ATP glucokinase from Mycobacterium tuberculosis. Biochemistry 32:6243-9
Kowalczyk, T H; Phillips, N F (1993) Determination of endopolyphosphatase using polyphosphate glucokinase. Anal Biochem 212:194-205
Phillips, N F (1988) The ATP/AMP binding site of pyruvate,phosphate dikinase: selective modification with fluorescein isothiocyanate. Biochemistry 27:3314-20

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