Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM029703-13
Application #
2175593
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1983-04-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Delaware
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
059007500
City
Newark
State
DE
Country
United States
Zip Code
19716
Pan, Ying H; Bahnson, Brian J (2010) Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2. Biochim Biophys Acta 1804:1443-8
Pan, Ying H; Bahnson, Brian J (2007) Structural basis for bile salt inhibition of pancreatic phospholipase A2. J Mol Biol 369:439-50
Tsai, Yu-Cheng; Yu, Bao-Zhu; Wang, Yu-Zhen et al. (2006) Desolvation map of the i-face of phospholipase A2. Biochim Biophys Acta 1758:653-65
Yu, Bao-Zhu; Pan, Ying H; Janssen, Marcel J W et al. (2005) Kinetic and structural properties of disulfide engineered phospholipase A2: insight into the role of disulfide bonding patterns. Biochemistry 44:3369-79
Bahnson, Brian J (2005) Structure, function and interfacial allosterism in phospholipase A2: insight from the anion-assisted dimer. Arch Biochem Biophys 433:96-106
Yu, Bao-Zhu; Polenova, Tatyana; Jain, Mahendra Kumar et al. (2005) Premicellar complexes of sphingomyelinase mediate enzyme exchange for the stationary phase turnover. Biochim Biophys Acta 1712:137-51
Berg, Otto G; Yu, Bao-Zhu; Chang, Cherry et al. (2004) Cooperative binding of monodisperse anionic amphiphiles to the i-face: phospholipase A2-paradigm for interfacial binding. Biochemistry 43:7999-8013
Berg, Otto G; Yu, Bao-Zhu; Apitz-Castro, Rafael J et al. (2004) Phosphatidylinositol-specific phospholipase C forms different complexes with monodisperse and micellar phosphatidylcholine. Biochemistry 43:2080-90
Cajal, Yolanda; Berg, Otto G; Jain, Mahendra Kumar (2004) Origins of delays in monolayer kinetics: phospholipase A2 paradigm. Biochemistry 43:9256-64
Yu, Bao-Zhu; Apitz-Castro, Rafael; Tsai, Ming-Daw et al. (2003) Interaction of monodisperse anionic amphiphiles with the i-face of secreted phospholipase A2. Biochemistry 42:6293-301

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