Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032007-10
Application #
2176407
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1985-05-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Albany Medical College
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Albany
State
NY
Country
United States
Zip Code
12208
Selden, L A; Kinosian, H J; Estes, J E et al. (1999) Impact of profilin on actin-bound nucleotide exchange and actin polymerization dynamics. Biochemistry 38:2769-78
Kinosian, H J; Newman, J; Lincoln, B et al. (1998) Ca2+ regulation of gelsolin activity: binding and severing of F-actin. Biophys J 75:3101-9
Selden, L A; Kinosian, H J; Newman, J et al. (1998) Severing of F-actin by the amino-terminal half of gelsolin suggests internal cooperativity in gelsolin. Biophys J 75:3092-100
Kinosian, H J; Selden, L A; Estes, J E et al. (1996) Kinetics of gelsolin interaction with phalloidin-stabilized F-actin. Rate constants for binding and severing. Biochemistry 35:16550-6
Gershman, L C; Selden, L A; Kinosian, H J et al. (1994) Actin-bound nucleotide/divalent cation interactions. Adv Exp Med Biol 358:35-49
Selden, L A; Kinosian, H J; Estes, J E et al. (1994) Influence of the high affinity divalent cation on actin tryptophan fluorescence. Adv Exp Med Biol 358:51-7
Kinosian, H J; Selden, L A; Estes, J E et al. (1993) Nucleotide binding to actin. Cation dependence of nucleotide dissociation and exchange rates. J Biol Chem 268:8683-91
Newman, J; Zaner, K S; Schick, K L et al. (1993) Nucleotide exchange and rheometric studies with F-actin prepared from ATP- or ADP-monomeric actin. Biophys J 64:1559-66
Herrmannsdoerfer, A J; Heeb, G T; Feustel, P J et al. (1993) Vascular clearance and organ uptake of G- and F-actin in the rat. Am J Physiol 265:G1071-81
Kinosian, H J; Selden, L A; Estes, J E et al. (1993) Actin filament annealing in the presence of ATP and phalloidin. Biochemistry 32:12353-7

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