Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032476-12
Application #
2176596
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1987-09-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Worcester Foundation for Biomedical Research
Department
Type
DUNS #
City
Shrewsbury
State
MA
Country
United States
Zip Code
01545
Zhang, Jian; Wang, Yu-Li (2017) Centrosome defines the rear of cells during mesenchymal migration. Mol Biol Cell 28:3240-3251
Zhang, Jian; Guo, Wei-Hui; Wang, Yu-Li (2014) Microtubules stabilize cell polarity by localizing rear signals. Proc Natl Acad Sci U S A 111:16383-8
Wong, Stephanie; Guo, Wei-Hui; Wang, Yu-Li (2014) Fibroblasts probe substrate rigidity with filopodia extensions before occupying an area. Proc Natl Acad Sci U S A 111:17176-81
Wong, Stephanie; Guo, Wei-hui; Hoffecker, Ian et al. (2014) Preparation of a micropatterned rigid-soft composite substrate for probing cellular rigidity sensing. Methods Cell Biol 121:3-15
Zhang, Jian; Guo, Wei-Hui; Rape, Andrew et al. (2013) Micropatterning cell adhesion on polyacrylamide hydrogels. Methods Mol Biol 1066:147-56
Chang, Stephanie S; Guo, Wei-hui; Kim, Youngeun et al. (2013) Guidance of cell migration by substrate dimension. Biophys J 104:313-21
Guo, Wei-hui; Wang, Yu-li (2012) A three-component mechanism for fibroblast migration with a contractile cell body that couples a myosin II-independent propulsive anterior to a myosin II-dependent resistive tail. Mol Biol Cell 23:1657-63
Rape, Andrew D; Guo, Wei-Hui; Wang, Yu-Li (2011) The regulation of traction force in relation to cell shape and focal adhesions. Biomaterials 32:2043-51
Rape, Andrew; Guo, Wei-hui; Wang, Yu-li (2011) Microtubule depolymerization induces traction force increase through two distinct pathways. J Cell Sci 124:4233-40
Hoffecker, Ian T; Guo, Wei-hui; Wang, Yu-li (2011) Assessing the spatial resolution of cellular rigidity sensing using a micropatterned hydrogel-photoresist composite. Lab Chip 11:3538-44

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