The aim of the proposed research is to exploit cloned sequences of Mul, a DNA element of maize transposed under the direction of Robertson's mutator, in order to analyze mutator and its mode of action. I plan to characterize the nature and distribution of the family of elements transposed by mutator, to identify the mutator controlling element, and to develop a system by which mutator-induced transposition can be studied in vitro.
Ortiz, D F; Rowland, L J; Gregerson, R G et al. (1988) Insertion of Mu into the Shrunken 1 gene of maize affects transcriptional and post-transcriptional regulation of Sh1 RNA. Mol Gen Genet 214:135-41 |
Rowland, L J; Strommer, J N (1986) Anaerobic treatment of maize roots affects transcription of Adh1 and transcript stability. Mol Cell Biol 6:3368-72 |