Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032892-10
Application #
2176780
Study Section
Metabolism Study Section (MET)
Project Start
1984-07-01
Project End
1998-03-31
Budget Start
1995-04-01
Budget End
1998-03-31
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
East Carolina University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Greenville
State
NC
Country
United States
Zip Code
27858
Yosefzon, Yahav; Koh, Yvonne Y; Chritton, Jacqueline J et al. (2011) Divergent RNA binding specificity of yeast Puf2p. RNA 17:1479-88
Qi, C; Pekala, P H (2000) Tumor necrosis factor-alpha-induced insulin resistance in adipocytes. Proc Soc Exp Biol Med 223:128-35
Jain, R G; Phelps, K D; Pekala, P H (1999) Tumor necrosis factor-alpha initiated signal transduction in 3T3-L1 adipocytes. J Cell Physiol 179:58-66
Jain, R; Police, S; Phelps, K et al. (1999) Tumour necrosis factor-alpha regulates expression of the CCAAT-enhancer-binding proteins (C/EBPs) alpha and beta and determines the occupation of the C/EBP site in the promoter of the insulin-responsive glucose-transporter gene in 3T3-L1 adipocytes. Biochem J 338 ( Pt 3):737-43
Jain, R G; Meredith, M J; Pekala, P H (1998) Tumor necrosis factor-alpha mediated activation of signal transduction cascades and transcription factors in 3T3-L1 adipocytes. Adv Enzyme Regul 38:333-47
McGowan, K M; Police, S; Winslow, J B et al. (1997) Tumor necrosis factor-alpha regulation of glucose transporter (GLUT1) mRNA turnover. Contribution of the 3'-untranslated region of the GLUT1 message. J Biol Chem 272:1331-7
Jain, R G; Andrews, L G; McGowan, K M et al. (1997) Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. Mol Cell Biol 17:954-62
Long, S D; Pekala, P H (1996) Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes. Biochem J 319 ( Pt 1):179-84
McGowan, K; Pekala, P H (1996) Dehydrogenase binding to the 3'-untranslated region of GLUT1 mRNA. Biochem Biophys Res Commun 221:42-5
Long, S D; Pekala, P H (1996) Regulation of GLUT4 gene expression by arachidonic acid. Evidence for multiple pathways, one of which requires oxidation to prostaglandin E2. J Biol Chem 271:1138-44

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